4,4'-二氨基二苯乙烯-2,2'-二磺酸
4,4'-二氨基二苯乙烯-2,2'-二磺酸结构式
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常用名 | 4,4'-二氨基二苯乙烯-2,2'-二磺酸 | 英文名 | 4,4′-Diamino-2,2′-stilbenedisulfonic acid |
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| CAS号 | 81-11-8 | 分子量 | 370.401 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C14H14N2O6S2 | 熔点 | 300 °C | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents.
Biol. Chem. 388(10) , 1069-81, (2007) We studied the effects of sulfur-containing chemopreventive agents, including allyl sulfides and isothiocyanates, on human redox networks. Isothiocyanates inhibited isolated redox-active enzymes in a time- and dose-dependent manner. As shown for the most acti... |
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Human SLC4A11-C functions as a DIDS-stimulatable H⁺(OH⁻) permeation pathway: partial correction of R109H mutant transport.
Am. J. Physiol. Cell Physiol. 308(2) , C176-88, (2015) The SLC4A11 gene mutations cause a variety of genetic corneal diseases, including congenital hereditary endothelial dystrophy 2 (CHED2), Harboyan syndrome, some cases of Fuchs' endothelial dystrophy (FECD), and possibly familial keratoconus. Three NH2-termina... |
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Uterotropic action in rats of amsonic acid and three of its synthetic precursors.
J. Toxicol. Environ. Health A 36(1) , 13-25, (1992) Prompted by reports of sexual impotence among chemical factory workers exposed to amsonic acid (4,4'-diaminostilbene-2,2'-disulfonic acid; CAS 81-11-8) and its synthetic precursors 4,4'-dinitrostilbene-2,2'-disulfonic acid (DNSDSA; CAS 128-42-7), 2-methyl-5-n... |
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Evaluation of the disodium salt of 4,4'-diamino-2,2'-stilbene disulfonic acid for estrogenic activity.
J. Toxicol. Environ. Health A 48(2) , 141-9, (1996) 4,4'-Diamino-2,2'-stilbene disulfonic acid (DAS), a key intermediate in the synthesis of dyes and fluorescent whitening agents, has been purported to have weak estrogenic properties based on apparent structural similarity with diethylstibestrol (DES) and unsu... |
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AE2 anion exchanger polypeptide is a homooligomer in pig gastric membranes: a chemical cross-linking study.
Biochemistry 38(26) , 8521-31, (1999) Although considerable information is available on the oligomeric states of the AE1 (band 3) anion exchanger, little is known about the physiological state of the polypeptides encoded by the nonerythroid AE genes, AE2 and AE3. We have previously characterized ... |
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Comparison of -nitro versus -amino 4,4'-substituents of disulfonic stilbenes as chloride channel blockers.
Mol. Cell Biochem. 140(2) , 137-46, (1994) We showed previously that the disulfonic stilbene DNDS (4,4'-dinitrostilben-2,2'-disulfonic acid) was a potent blocker of outwardly rectifying chloride channels (ORCC). The studies reported here were designed to quantify the relationship between electron with... |
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Disulfonic stilbene prevents selenite-induced cataract in rat pup lens.
Biol. Trace Elem. Res. 75(1-3) , 129-38, (2000) It is known that the subcutaneous injection of a single dose of sodium selenite into suckling rats results in the development of large nuclear opacities. The intracellular transport of selenite in various cells, except lens cells, occurs via the Cl/HCO3 excha... |
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Prediction of the rodent carcinogenicity of organic compounds from their chemical structures using the FALS method.
Environ. Health Perspect. 104 Suppl 5 , 1051-8, (1996) Fuzzy adaptive least-squares (FALS), a pattern recognition method recently developed in our laboratory for correlating structure with activity rating, was used to generate quantitative structure-activity relationship (QSAR) models on the carcinogenicity of or... |
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Anion transport across the red blood cell membrane and the conformation of the protein in Band 3.
Ann. N. Y. Acad. Sci. 341 , 361-83, (1980) Measuring the rate of dinitrophenylation of a specific lysine residue (called a) that is allosterically linked to the transfer site, it could be demonstrated that the anion transport protein may exist in two different conformational states, designated cis and... |
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[Experimental studies on rat ear duct tumor. Part 2: Effects of anticancer drugs on rat ear duct tumor induced by DMBA and DAS (author's transl)].
Nippon. Jibiinkoka Gakkai Kaiho 83(7) , 757-68, (1980)
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