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苯菌灵

一般危化品
苯菌灵结构式
苯菌灵结构式
常用名 苯菌灵 英文名 Benomyl
CAS号 17804-35-2 分子量 290.318
密度 1.3±0.1 g/cm3 沸点 N/A
分子式 C14H18N4O3 熔点 >300 °C(lit.)
MSDS 中文版 美版 闪点 N/A
符号 GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
信号词 Danger

Determination of manganese- and manganese-containing fungicides with lucigenin-Tween-20-enhanced chemiluminescence detection.

Luminescence 30 , 950-61, (2015)

A flow-injection (FI) method is reported for the determination of Mn(II), maneb and mancozeb fungicides based on the catalytic effect of Mn(II) on the oxidation of lucigenin and dissolved oxygen in a basic solution. The Tween-20 surfactant has been reported f...

Development of a high-efficiency gene knockout system for Pochonia chlamydosporia.

Microbiol. Res. 170 , 18-26, (2014)

The nematophagous fungus Pochonia chlamydosporia, which belongs to the family Clavicipitaceae (Ascomycota: Pezizomycotina: Sordariomycetes: Hypocreales), is a promising biological control agent for root-knot and cyst nematodes. Its biocontrol effect has been ...

Role of BGT-1 and BGT-2, two predicted GPI-anchored glycoside hydrolases/glycosyltransferases, in cell wall remodeling in Neurospora crassa.

Fungal Genet. Biol. 85 , 58-70, (2015)

Neurospora crassa BGT-1 (NCU06381) and BGT-2 (NCU09175) are two putative glycoside hydrolases (GHs) with additional predicted glycosyltransferase activity and binding sites for a glycosyl phosphatidyl inositol (GPI) anchor that would facilitate their attachme...

Influence of the carbamate fungicide benomyl on the gene expression and activity of aromatase in the human breast carcinoma cell line MCF-7.

Environ. Toxicol. Pharmacol. 39(1) , 292-9, (2015)

The carbamate fungicide benomyl reportedly inhibited the growth of the human breast cancer cell line MCF-7 by inducing apoptosis. However, influence of benomyl on the expression and activity of aromatase of MCF-7 cells remains to be examined, since benomyl wa...

Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.

Eur. J. Med. Chem. 45 , 4813-26, (2010)

In this study, we have explored the structure activity relationships of substrates of two major, promiscuous, multidrug transporters of an opportunistic human pathogen Candida albicans namely, CaCdr1p and CaMdr1p. To differentiate between substrates and non-s...

Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Nat. Struct. Mol. Biol. 15(8) , 873-80, (2008)

SWI/SNF chromatin-remodeling complexes have crucial roles in transcription and other chromatin-related processes. The analysis of the two members of this class in Saccharomyces cerevisiae, SWI/SNF and RSC, has heavily contributed to our understanding of these...

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009)

The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and ketone inhibitors of fatty acid amide hydrolase (FAAH) have bee...

A Candida albicans petite mutant strain with uncoupled oxidative phosphorylation overexpresses MDR1 and has diminished susceptibility to fluconazole and voriconazole.

Antimicrob. Agents Chemother. 51 , 1855-8, (2007)

We showed that a Candida albicans petite mutant in which oxidative phosphorylation is uncoupled was eightfold more resistant to fluconazole and voriconazole than SC5314 but equally susceptible to ketoconazole, itraconazole, and amphotericin B. Strain P5 signi...

Antiandrogenic mechanisms of pesticides in human LNCaP prostate and H295R adrenocortical carcinoma cells.

Toxicol. Sci. 143(1) , 126-35, (2014)

Several pesticides suspected or known to have endocrine disrupting effects were screened for pro- or antiandrogenic properties by determining their effects on proliferation, prostatic-specific antigen (PSA) secretion and androgen receptor (AR) expression, and...

Validation of earthworm toxicity tests by comparison with field studies: a review of benomyl, carbendazim, carbofuran, and carbaryl.

Ecotoxicol. Environ. Saf. 23(2) , 221-36, (1992)

To investigate whether results of laboratory toxicity tests with earthworms are capable of being used to predict effects in the field, a literature study was carried out. Benomyl, its metabolite carbendazim, carbofuran, and carbaryl were chosen as model subst...