凝血酸，氨甲环酸
凝血酸，氨甲环酸结构式
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常用名 | 凝血酸，氨甲环酸 | 英文名 | Tranexamic acid |
|---|---|---|---|---|
| CAS号 | 1197-18-8 | 分子量 | 157.210 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 300.2±15.0 °C at 760 mmHg | |
| 分子式 | C8H15NO2 | 熔点 | >300 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 135.4±20.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Long-Term Mild, rather than Intense, Exercise Enhances Adult Hippocampal Neurogenesis and Greatly Changes the Transcriptomic Profile of the Hippocampus.
PLoS ONE 10 , e0128720, (2015) Our six-week treadmill running training (forced exercise) model has revealed that mild exercise (ME) with an intensity below the lactate threshold (LT) is sufficient to enhance spatial memory, while intense exercise (IE) above the LT negates such benefits. To... |
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Design, Synthesis, and Photophysical Properties of Pyrroloquinoline-Based Compounds Showing Strong Blue Fluorescence as Potential Dyes for Biomedical Applications.
ChemMedChem 10 , 1846-62, (2015) A small library of 3-ethylpyrrolo[3,2-f]quinoline derivatives was synthesized to identify a novel class of dyes for use in biological studies. According to the spectroscopic analyses performed to evaluate the fluorimetric parameters of quantum yield and brigh... |
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Lapatinib-incorporated lipoprotein-like nanoparticles: preparation and a proposed breast cancer-targeting mechanism.
Acta Pharmacol. Sin. 35(6) , 846-52, (2014) Lapatinib is a dual inhibitor of EGFR and human epidermal growth factor receptor 2 (HER2), and used to treat advanced breast cancer. To overcome its poor water solubility, we constructed lapatinib-incorporated lipoprotein-like nanoparticles (LTNPs), and evalu... |
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Distribution and density of contacts from noradrenergic and serotonergic boutons on the dendrites of neck flexor motoneurons in the adult cat.
J. Comp. Neurol. 523 , 1701-16, (2015) Serotonergic (5-HT) and noradrenergic (NA) input to spinal motoneurons is essential for generating plateau potentials and self-sustained discharges. Extensor motoneurons are densely innervated by 5-HT and NA synapses and have robust plateau potentials and sel... |
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Prion protein-deficient mice exhibit decreased CD4 T and LTi cell numbers and impaired spleen structure.
Immunobiology 221 , 94-102, (2015) The cellular prion protein is expressed in almost all tissues, including the central nervous system and lymphoid tissues. To investigate the effects of the prion protein in lymphoid cells and spleen structure formation, we used prion protein-deficient (Prnp(0... |
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Effect of tranexamic acid irrigation on perioperative blood loss during orthognathic surgery: a double-blind, randomized controlled clinical trial.
J. Oral Maxillofac. Surg. 73(1) , 129-33, (2015) Perioperative hemorrhage is an important concern during orthognathic surgery. The purpose of this study was to assess the effect of tranexamic acid (TXA) irrigation on perioperative hemorrhage during orthognathic surgery.In this double-blind, randomized contr... |
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Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
J. Bone Joint Surg. Am. 96(23) , 1937-44, (2014) Abundant literature regarding the use of intravenous tranexamic acid (TXA) in primary total knee replacement is available. Randomized controlled trials have confirmed the efficacy of topical TXA compared with placebo, but the comparison between topical and in... |
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Downregulation of the microtubule associated protein tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes.
Glia 63 , 1621-35, (2015) Oligodendrocytes, the myelin forming cells of the CNS, are characterized by their numerous membranous extensions, which enwrap neuronal axons and form myelin sheaths. During differentiation oligodendrocytes pass different morphological stages, downregulate th... |
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A spontaneous animal model of intestinal dysmotility evoked by inflammatory nitrergic dysfunction.
PLoS ONE 9(5) , e95879, (2014) Recent reports indicate the presence of low grade inflammation in functional gastrointestinal disorders (FGID), in these cases often called "post-inflammatory" FGIDs. However, suitable animal models to study these disorders are not available. The Biobreeding ... |
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Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission.
Nature 511(7508) , 236-40, (2014) Although considerable evidence suggests that the chemical synapse is a lynchpin underlying affective disorders, how molecular insults differentially affect specific synaptic connections remains poorly understood. For instance, Neurexin 1a and 2 (NRXN1 and NRX... |