前往化源商城

腺苷酸二钠盐

腺苷酸二钠盐结构式
腺苷酸二钠盐结构式
品牌特惠专场
常用名 腺苷酸二钠盐 英文名 Adenosine 5′-monophosphate disodium salt
CAS号 4578-31-8 分子量 391.185
密度 N/A 沸点 798.5ºC at 760 mmHg
分子式 C10H12N5Na2O7P 熔点 232-235ºC
MSDS 美版 闪点 436.7ºC

Regulation of AMPK by the ubiquitin proteasome system.

Am. J. Pathol. 178 , 4-11, (2011)

The 5'-AMP-activated protein kinase (AMPK) functions as a metabolic fuel gauge that is activated in response to environmental stressors to restore cellular energy balance. In the heart, AMPK coordinates the activation of glucose and fatty acid metabolic pathw...

New strategies in prostate cancer: targeting lipogenic pathways and the energy sensor AMPK.

Clin. Cancer Res. 16 , 3322-3328, (2010)

Although the role of metabolic syndrome (MS) and a high fat diet in prostate cancer (PCa) risk is still a matter of intense debate, it is becoming increasingly clear that obesity can cause perturbations in metabolic pathways that contribute to the pathogenesi...

Identification of a novel CaMKK substrate.

Biochem. Biophys. Res. Commun. 410 , 45-51, (2011)

Ca(2+)/calmodulin-dependent protein kinase kinase (CaMKK) phosphorylates and activates specific downstream protein kinases including CaMKI, CaMKIV and 5'-AMP-activated protein kinase. In order to examine the variety of CaMKK-mediated signaling pathways, we se...

Sensitive and validated LC-MS/MS methods to evaluate mycophenolic acid pharmacokinetics and pharmacodynamics in hematopoietic stem cell transplant patients.

Biomed. Chromatogr. 29 , 1309-16, (2015)

Monitoring of pharmacodynamics in addition to pharmacokinetics is one of strategies to individualize mycophenolate mofetil therapy. The purpose of this study was to develop sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for evalua...

AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver.

PLoS ONE 10 , e0124951, (2015)

Our previous study found that thyroid-stimulating hormone promoted sterol regulatory element-binding protein-2 (SREBP-2) expression and suppressed AMP-activated protein kinase (AMPK) activity in the liver, but it was unclear whether there was a direct link be...

5′-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes. Tsuchiya Y, Denison FC, et al.

Biosci. Rep. 32(2) , 197-213, (2011)