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Oxamflatin

Oxamflatin结构式
Oxamflatin结构式
品牌特惠专场
常用名 Oxamflatin 英文名 Oxamflatin
CAS号 151720-43-3 分子量 342.369
密度 1.4±0.1 g/cm3 沸点 N/A
分子式 C17H14N2O4S 熔点 N/A
MSDS 中文版 美版 闪点 N/A

Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition.

Hum. Mol. Genet. 18 , 304-17, (2009)

Spinal muscular atrophy (SMA), a common neuromuscular disorder, is caused by homozygous absence of the survival motor neuron gene 1 (SMN1), while the disease severity is mainly influenced by the number of SMN2 gene copies. This correlation is not absolute, su...