Oxamflatin
Oxamflatin structure
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Common Name | Oxamflatin | ||
|---|---|---|---|---|
| CAS Number | 151720-43-3 | Molecular Weight | 342.369 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C17H14N2O4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition.
Hum. Mol. Genet. 18 , 304-17, (2009) Spinal muscular atrophy (SMA), a common neuromuscular disorder, is caused by homozygous absence of the survival motor neuron gene 1 (SMN1), while the disease severity is mainly influenced by the number of SMN2 gene copies. This correlation is not absolute, su... |
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