佐替平
佐替平结构式
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常用名 | 佐替平 | 英文名 | Zotepine |
|---|---|---|---|---|
| CAS号 | 26615-21-4 | 分子量 | 331.86 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 478.4±45.0 °C at 760 mmHg | |
| 分子式 | C18H18ClNOS | 熔点 | 90-91 °C | |
| MSDS | 中文版 美版 | 闪点 | 243.2±28.7 °C | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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Safety evaluation of zotepine for the treatment of schizophrenia.
Expert Opin. Drug Saf. 9(4) , 659-66, (2010) Atypical antipsychotics have become the first-line treatment for patients suffering from schizophrenia in the industrialized world. Given the frequent necessity of a life-long enduring antipsychotic treatment, the compounds' safety profile is of great importa... |
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Zotepine for schizophrenia.
Cochrane Database Syst. Rev. (4) , CD001948, (2006) Zotepine is a relatively new antipsychotic often used for the treatment of people with schizophrenia. It is claimed to be particularly effective for negative symptoms.To determine the effects of zotepine compared with placebo, typical and other atypical antip... |
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Differences in the effect of second-generation antipsychotics on prolactinaemia: six weeks open-label trial in female in-patients.
Neuro Endocrinol. Lett. 28(6) , 881-8, (2007) The main objective was to evaluate the effect of five second-generation antipsychotics (amisulpride, quetiapine, olanzapine, risperidone, and zotepine) on prolactinaemia during 6 week therapy in 433 female in-patients with mainly schizophrenic disorders. Seco... |
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Zotepine-induced spontaneous ejaculation.
Int. J. Clin. Pharmacol. Ther. 46(11) , 571-3, (2008) A man with schizophrenia received regular haloperidol ester therapy, but his psychotic symptoms were not mitigated. A combination of zotepine and haloperidol was then used to relieve the psychotic symptoms. However, the patient developed spontaneous ejaculati... |
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Rifampin-zotepine interaction reduces effectiveness of antipsychotic drugs in a stable schizophrenia patient.
Psychiatry Clin. Neurosci. 66(6) , 538, (2012)
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Zotepine-related myopathy in a patient with schizophrenia.
Eur. J. Clin. Pharmacol. 69(3) , 725-6, (2013)
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Hyperhidrosis under combination of zotepine and haloperidol alleviated by aripiprazole.
Psychiatry Clin. Neurosci. 66(3) , 245, (2012)
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Improvement in QTc prolongation induced by zotepine following a switch to perospirone.
Psychiatry Clin. Neurosci. 66(3) , 244, (2012)
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Valproate and high dosage of zotepine induced acute delirium: a case report.
Br. J. Clin. Pharmacol. 73(3) , 486-8, (2012)
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A self-limiting case of atypical neuroleptic malignant syndrome associated with zotepine.
J. Clin. Psychopharmacol. 31(5) , 667-9, (2011)
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