1,3-双(4-羧基苯氧基)丙烷
1,3-双(4-羧基苯氧基)丙烷结构式
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常用名 | 1,3-双(4-羧基苯氧基)丙烷 | 英文名 | 1 3-BIS(P-CARBOXYPHENOXY)PROPANE |
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| CAS号 | 3753-81-9 | 分子量 | 316.30500 | |
| 密度 | 1.318g/cm3 | 沸点 | 533.5ºC at 760 mmHg | |
| 分子式 | C17H16O6 | 熔点 | 310ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 196.7ºC | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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One type of novel thermosensitive polymeric micelles
J. Control. Release 152 Suppl 1 , e127-8, (2011)
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Design of an injectable system based on bioerodible polyanhydride microspheres for sustained drug delivery.
Biomaterials 23 , 4405, (2002) The fabrication, morphological characterization, and drug release kinetics from microspheres of three bioerodible polyanhydrides, poly[1,6-bis(p-carboxyphenoxy)hexane] (poly(CPH)), poly(sebacic anhydride) (poly(SA)), and the copolymer poly(CPH-co-SA) 50:50 (C... |
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Urich, K.E. et al.
Macromolecules 28 , 2184, (1995)
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Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain.
Biomaterials 15(9) , 681-8, (1994) The metabolic disposition and elimination process of the anhydride co-polymer poly[1,3-bis(p-carboxy-phenoxypropane):sebacic acid] 20:80 [P(CPP:Sa)20:80] implanted in the rat brain was studied. Two polymers were prepared, one with [14C]SA and unlabelled CPP, ... |
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Excretion of a radiolabelled anticancer biodegradable polymeric implant from the rabbit brain.
Biomaterials 16(14) , 1069-72, (1995) The elimination of a clinically used anticancer biodegradable polymer implant (Gliadel) in the rabbit brain was studied. The implant is composed of N,N-bis(2-chloroethyl)-N-nitrosourea (BCNU) (1.6 wt%) dispersed in a copolyanhydride matrix of 1,3-bis(p-carbox... |
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Molecular weight changes in polymer erosion.
Pharm. Res. 9(10) , 1279-83, (1992) We report a study of the effects of polymer molecular weight on the erosion of polyanhydride copolymer matrices composed of 1,3-bis(p-carboxyphenoxy)-propane (CPP) and sebacic acid (SA) in aqueous solution. The erosion profile characteristically displays an i... |
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Pulsatile release of parathyroid hormone from an implantable delivery system.
Biomaterials 28(28) , 4124-31, (2007) Intermittent (pulsatile) administration of parathyroid hormone (PTH) is known to improve bone micro-architecture, mineral density and strength. Therefore, daily injection of PTH has been clinically used for the treatment of osteoporosis. However, this regimen... |
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Comparison of metabolic effects of ziprasidone versus olanzapine treatment in patients with first-episode schizophrenia.
Macromol. Biosci. 7(5) , 620-8, (2007) The objective of the study was to compare metabolic effects of ziprasidone versus olanzapine treatment in patients with first-episode schizophrenia.In this 6-week, multicenter, open-label trial, 260 patients were randomly assigned to receive ziprasidone or ol... |
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Synthesis and characterization of polyanhydride for local BCNU delivery carriers.
Biomed Mater Eng 15(3) , 229-38, (2005) p-Carboxyphenoxy propane (CPP) prepolymer consisting of 4 units and sebacic acid (SA) prepolymer consisting of about 10 units were synthesized by reacting CPP and SA in the presence of excess acetic anhydride, respectively. Polyanhydride, poly(CPP-SA) copolym... |