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5-氨基-3-(4-甲氧苯基)-1-苯基吡唑

5-氨基-3-(4-甲氧苯基)-1-苯基吡唑结构式
5-氨基-3-(4-甲氧苯基)-1-苯基吡唑结构式
品牌特惠专场
常用名 5-氨基-3-(4-甲氧苯基)-1-苯基吡唑 英文名 3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE
CAS号 19652-13-2 分子量 265.31000
密度 1.192g/cm3 沸点 483.568ºC at 760 mmHg
分子式 C16H15N3O 熔点 192-196ºC(lit.)
MSDS 中文版 美版 闪点 246.254ºC
符号 GHS07
GHS07
信号词 Warning

Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-α and IL-6 inhibitors

Bioorg. Med. Chem. 16 , 7167-76, (2008)

Three different series of pyrazolo[3,4- b]pyridines were synthesized and evaluated for their anti-inflammatory activity against TNF-α and IL-6. Several compounds showed promising IL-6 inhibitory activity, amongst which most potent analogue has IC 50 0.16 μM a...

Approaches towards the synthesis of 5-aminopyrazoles. Aggarwal R, et al.

Beilstein J. Org. Chem. 7(1) , 179-197, (2011)