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4-硝基吲哚-3-甲醛

4-硝基吲哚-3-甲醛结构式
4-硝基吲哚-3-甲醛结构式
品牌特惠专场
常用名 4-硝基吲哚-3-甲醛 英文名 4-nitro-1H-indole-3-carbaldehyde
CAS号 10553-11-4 分子量 190.15600
密度 1.517g/cm3 沸点 441.47ºC at 760 mmHg
分子式 C9H6N2O3 熔点 189-193ºC
MSDS 美版 闪点 220.794ºC
符号 GHS07
GHS07
信号词 Warning

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.

J. Med. Chem. 54 , 5320, (2011)

Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance. IDO inhibition is thus an active area of research in drug development. Recently, our group ...

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