DC-胆固醇
DC-胆固醇结构式
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常用名 | DC-胆固醇 | 英文名 | DC-cholesterol hydrochloride |
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| CAS号 | 166023-21-8 | 分子量 | 537.26000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C32H57ClN2O2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE.
Gene Ther. 2 , 603-613, (1995) Clinical trials using cationic liposome-mediated DNA transfer have now been initiated for several disorders including cystic fibrosis. Previous studies have shown that the level of gene expression achieved may be dependent on the formulation of the DNA-liposo... |
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Lipofection reagents prepared by a simple ethanol injection technique.
Biotechniques 18 , 1027-1032, (1995) Cationic liposomes are being utilized for the delivery of DNA into mammalian cells both in vitro and in vivo. In this report, we describe a rapid, simple injection method for the preparation of cationic liposomes that requires no special equipment. We demonst... |
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The use of cationic liposomes DC-CHOL/DOPE and DDAB/DOPE for direct transfer of Escherichia coli cytosine deaminase gene into growing melanoma tumors.
Gene Ther. 3 , 1026-1031, (1996) An attempt was made to use simple cationic liposomes DC-Chol/DOPE and DDAB/DOPE (DC-Chol is 3 beta (N(N',N-dimethylaminoethane) carbamoyl) cholesterol, DDAB is dimethyldioctadecyl ammonium bromide and DOPE is dioleoylphosphatidylethanolamine) for transfer of ... |
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A novel cationic liposome reagent for efficient transfection of mammalian cells.
Biochem. Biophys. Res. Commun. 179 , 280, (1991) A novel cationic derivative of cholesterol, 3 beta [N-(N',N'-dimethylaminoethane)-carbamoyl] cholesterol (DC-Chol), has been synthesized and used to prepare sonicated liposomes with dioleoylphosphatidylethanolamine. This novel cationic liposome reagent facili... |
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Gene transfection efficiency of tracheal epithelial cells by DC-chol-DOPE/DNA complexes.
Biochim. Biophys. Acta 1419 , 186, (1999) We evaluated the transfection efficiency of five different cationic liposome/plasmid DNA complexes, during the in vitro gene transfer into human epithelial tracheal cell lines. A dramatic correlation between the transfection efficiency and the charge ratio (p... |
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3Beta [N-(N',N'-dimethylaminoethane)-carbamoyl] cholesterol (DC-Chol)-mediated gene delivery to primary rat neurons: characterization and mechanism.
Neurochem. Res. 24 , 699-703, (1999) Cationic lipid formulations consisting of 3beta [N-(N', N'-dimethylaminoethane)-carbamoyl] cholesterol (DC-Chol) and the helper lipid dioleoylphosphatidylethanolamine (DOPE) (1.5: 1 molar ratio) were prepared by solvent evaporation and sized by high pressure ... |