DC-胆固醇

更新时间：2024-01-02 16:28:13

DC-胆固醇结构式	常用名	DC-胆固醇	英文名	DC-cholesterol hydrochloride
	CAS号	166023-21-8	分子量	537.26000
	密度	N/A	沸点	N/A
	分子式	C₃₂H₅₇ClN₂O₂	熔点	N/A
	MSDS	美版	闪点	N/A

DC-胆固醇用途

在合适的实验条件下,DC-Chol盐酸盐能抑制Aβ40原纤维的形成。DC-Chol盐酸盐以剂量依赖性方式强烈抑制氧化hCT的淀粉样变性[1][2]。

中文名	O-[(N,N-二甲基氨基乙基)-氨基甲酰基]胆固醇盐酸盐
英文名	Cholest-5-en-3-yl [2-(dimethylamino)ethyl]carbamate hydrochloride (1:1)
中文别名	DC-胆固醇
英文别名	更多

描述	在合适的实验条件下,DC-Chol盐酸盐能抑制Aβ40原纤维的形成。DC-Chol盐酸盐以剂量依赖性方式强烈抑制氧化hCT的淀粉样变性[1][2]。
相关类别	研究领域 >> 神经疾病
参考文献	[1]. Esmail A Elbassal, et al. Effects of Charged Cholesterol Derivatives on Aβ40 Amyloid Formation. J Phys Chem B. 2016 Jan 14;120(1):59-68. [2]. Richard Lantz, et al. Effects of disulfide bond and cholesterol derivatives on human calcitonin amyloid formation. Biopolymers. 2020 May;111(5):e23343.

描述

在合适的实验条件下,DC-Chol盐酸盐能抑制Aβ40原纤维的形成。DC-Chol盐酸盐以剂量依赖性方式强烈抑制氧化hCT的淀粉样变性[1][2]。

相关类别

研究领域 >> 神经疾病

参考文献

[1]. Esmail A Elbassal, et al. Effects of Charged Cholesterol Derivatives on Aβ40 Amyloid Formation. J Phys Chem B. 2016 Jan 14;120(1):59-68.

[2]. Richard Lantz, et al. Effects of disulfide bond and cholesterol derivatives on human calcitonin amyloid formation. Biopolymers. 2020 May;111(5):e23343.

分子式	C₃₂H₅₇ClN₂O₂
分子量	537.26000
精确质量	536.41100
PSA	45.06000
LogP	8.69060
外观性状	白色粉末
储存条件	-20℃，密封，干燥

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport
WGK德国	3

In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE.

Gene Ther. 2 , 603-613, (1995)

Clinical trials using cationic liposome-mediated DNA transfer have now been initiated for several disorders including cystic fibrosis. Previous studies have shown that the level of gene expression ach...

Lipofection reagents prepared by a simple ethanol injection technique.

Biotechniques 18 , 1027-1032, (1995)

Cationic liposomes are being utilized for the delivery of DNA into mammalian cells both in vitro and in vivo. In this report, we describe a rapid, simple injection method for the preparation of cation...

The use of cationic liposomes DC-CHOL/DOPE and DDAB/DOPE for direct transfer of Escherichia coli cytosine deaminase gene into growing melanoma tumors.

Gene Ther. 3 , 1026-1031, (1996)

An attempt was made to use simple cationic liposomes DC-Chol/DOPE and DDAB/DOPE (DC-Chol is 3 beta (N(N',N-dimethylaminoethane) carbamoyl) cholesterol, DDAB is dimethyldioctadecyl ammonium bromide and...

2,3-dihydroxypropyl dihydrogen phosphate-cyclohexanamine(2:1)

DC-cholesterol hydrochloride

marinobufotoxin

3β-[N-(Dimethylaminoethane)carbamoyl]cholesterol

O-[(N,N-Dimethylaminoethyl)-carbamoyl]cholesterol hydrochloride