D(+)-组胺醇二盐酸盐
D(+)-组胺醇二盐酸盐结构式
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常用名 | D(+)-组胺醇二盐酸盐 | 英文名 | d(+)-histidinol dihydrochloride |
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| CAS号 | 75614-84-5 | 分子量 | 214.093 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C6H13Cl2N3O | 熔点 | 193-195ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.
J. Biol. Chem. 286 , 403-9, (2011) Topoisomerase II (Top2) activity involves an intermediate in which the topoisomerase is covalently bound to a DNA double-strand break via a 5'-phosphotyrosyl bond. Although these intermediates are normally transient, they can be stabilized by antitumor agents... |
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