BOC-L-脯氨醇
BOC-L-脯氨醇结构式
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常用名 | BOC-L-脯氨醇 | 英文名 | N-Boc-L-Prolinol |
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| CAS号 | 69610-40-8 | 分子量 | 201.26 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 289.5±13.0 °C at 760 mmHg | |
| 分子式 | C10H19NO3 | 熔点 | 60-64ºC | |
| MSDS | 中文版 美版 | 闪点 | 128.9±19.8 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites.
Bioorg. Med. Chem. 12 , 2099-2114, (2004) Since factor Xa (fXa) plays a pivotal role in the blood coagulation cascade, inhibition of fXa is thought to be an effective treatment for a variety of thrombotic events. (2S)-2-[4-[[(3S)-1-Acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-(7-amidino-2-naphthyl)propan... |
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Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.
J. Med. Chem. 39 , 817-825, (1996) Recent evidence indicating the therapeutic potential of cholinergic channel modulators for the treatment of central nervous system (CNS) disorders as well as the diversity of brain neuronal nicotine acetylcholine receptors (nAChRs) have suggested an opportuni... |
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Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.
J. Med. Chem. 40 , 385, (1997) 2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine, ABT-089 (S-4), a member of the 3-pyridyl ether class of nicotinic acetylcholine receptor (nAChR) ligands, shows positive effects in rodent and primate models of cognitive enhancement and a rodent model of anxioly... |
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Elliott, R.L. et al.
Bioorg. Med. Chem. Lett. 6 , 2283, (1996)
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Cran, G.A. et al.
Tetrahedron Asymmetry 6 , 1553, (1995)
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