盐酸去氧肾上腺素(苯肾上腺素杂质A)
盐酸去氧肾上腺素(苯肾上腺素杂质A)结构式
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常用名 | 盐酸去氧肾上腺素(苯肾上腺素杂质A) | 英文名 | Norphenylephrine hydrochloride |
|---|---|---|---|---|
| CAS号 | 4779-94-6 | 分子量 | 189.64 | |
| 密度 | 1.249g/cm3 | 沸点 | 360.7ºC at 760mmHg | |
| 分子式 | C8H12ClNO2 | 熔点 | 162-164ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 172ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Selective synthesis of racemic 1-11C-labelled norepinephrine, octopamine, norphenylephrine and phenylethanolamine using [11C]nitromethane.
Appl. Radiat. Isot. 45(4) , 515-21, (1994) A new and simple method for the selective condensation of no-carrier-added [11C]nitromethane (1) with various substituted (protected) benzaldehydes to [beta-11C]beta-nitrophenethyl alcohols was developed. This method which utilizes tetrabutylammonium fluoride... |
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Chiral separations on multichannel microfluidic chips.
Electrophoresis 26(24) , 4774-9, (2005) Chiral separations of FITC-labeled basic drugs on multichannel microfluidic chips with LIF detector were investigated. A preliminary screening procedure for seven neutral CDs was performed under optimized conditions for chiral separations of three FITC-labele... |
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In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects.
J. Pharmacol. Exp. Ther. 301(1) , 229-33, (2002) The role of alpha(1)-adrenoceptors in lipid mobilization and blood flow was investigated in situ using microdialysis of subcutaneous adipose tissue in severely obese subjects. The lipolysis rate was assessed by determination of interstitial glycerol concentra... |
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[Therapy of hypotension in pregnancy using norfenefrine hydrochloride with special reference to the effects on fetal circulation--initial observations].
Z. Geburtshilfe Perinatol. 196(1) , 21-5, (1992) Hypotension in pregnancy represents an often underestimated danger for mother and fetus. Several investigators have described an increased incidence of miscarriages, premature delivery and small for date babies. In a first study 10 pregnant women with hypoten... |
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The effects of m-octopamine on salivary flow rates and protein secretion by rat submandibular glands.
Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. 103(3) , 469-76, (1992) 1. m-Octopamine given i.v. or i.p. was a potent sialogogue for rat salivary glands. 2. Salivation in response to i.v. m-octopamine was completely abolished by prazosin and phenoxybenzamine. 3. The alpha-type of proteins were secreted in response to all doses ... |
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[Problems in carrying out baroreflex sensitivity measurements in clinical routine practice: practicability and complications].
Z. Kardiol. 86(3) , 165-70, (1997) Measurement of baroreflex sensitivity is a new method to identify patients after myocardial infarction with a high risk for sudden cardiac death, ventricular tachycardia or ventricular fibrillation. In this retrospective study the baroreflex sensitivity was o... |
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Direct chiral resolution of phenylalkylamines using a crown ether chiral stationary phase.
Biomed. Chromatogr. 11(1) , 7-10, (1997) A direct, isocratic high-performance liquid chromatographic method is described for the enantiomeric resolution of a number of phenylalkylamines, namely, racemic cathinone, amphetamine, norephedrine, and norphenylephrine, without sample derivatization. The se... |
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Acute effect of norfenefrine on the urethral pressure profile in females with genuine stress incontinence.
Urol. Int. 46(2) , 176-9, (1991) To study the acute effect of norfenefrine, given orally in aqueous solution, on the urethral closure function, profilometry was performed before and after administration of placebo and increasing doses of norfenefrine in 6 females with genuine stress incontin... |
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Central administration of p-octopamine to mice: assessment of antinociception.
Eur. J. Pharmacol. 169(2-3) , 317-20, (1989) Administration of p-octopamine by intracerebroventricular (i.c.v.) or intrathecal (i.t.) routes, but not orally, produced antinociception in the acetylcholine-induced abdominal constriction test (ED50 = 24.8 and 3.6 micrograms, respectively). Likewise, i.c.v.... |
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Roles of MMP-2/-9 in cardiac dysfunction during early multiple organ failure in an ovine animal model.
Pathol. Res. Pract. 201(12) , 809-17, (2005) Biventricular dilation and severe cardiac dysfunction are observed during septic shock. However, when endotoxemia and vasoconstrictor-masked hypovolemia work in concert in the pathogenesis of shock, the clinical scenario is more adverse compared to one of the... |