4-烯丙基儿茶酚; 4-(2-丙烯基)-1,2-苯二醇; 4-烯丙基-1,2-苯二醇
4-烯丙基儿茶酚; 4-(2-丙烯基)-1,2-苯二醇; 4-烯丙基-1,2-苯二醇结构式
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常用名 | 4-烯丙基儿茶酚; 4-(2-丙烯基)-1,2-苯二醇; 4-烯丙基-1,2-苯二醇 | 英文名 | 4-allylcatechol |
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| CAS号 | 1126-61-0 | 分子量 | 150.174 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 289.2±25.0 °C at 760 mmHg | |
| 分子式 | C9H10O2 | 熔点 | 42.0 to 46.0 °C | |
| MSDS | 中文版 美版 | 闪点 | 141.7±17.8 °C |
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A new hydroxychavicol dimer from the roots of Piper betle.
Molecules 18(3) , 2563-70, (2013) A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadio... |
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Piper betel leaf extract: anticancer benefits and bio-guided fractionation to identify active principles for prostate cancer management.
Carcinogenesis 34(7) , 1558-66, (2013) Plant extracts, a concoction of bioactive non-nutrient phytochemicals, have long served as the most significant source of new leads for anticancer drug development. Explored for their unique medicinal properties, the leaves of Piper betel, an evergreen perenn... |
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Evaluation of the antimicrobial, antioxidant, and anti-inflammatory activities of hydroxychavicol for its potential use as an oral care agent.
Antimicrob. Agents Chemother. 53 , 216-22, (2009) Hydroxychavicol isolated from the chloroform extraction of aqueous extract of Piper betle leaves showed inhibitory activity against oral cavity pathogens. It exhibited an inhibitory effect on all of the oral cavity pathogens tested (MICs of 62.5 to 500 microg... |
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Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle.
J. Nat. Med. 63(3) , 355-9, (2009) The screening of Piperaceous plants for xanthine oxidase inhibitory activity revealed that the extract of the leaves of Piper betle possesses potent activity. Activity-guided purification led us to obtain hydroxychavicol as an active principle. Hydroxychavico... |
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Modulation of Th1/Th2 cytokines and inflammatory mediators by hydroxychavicol in adjuvant induced arthritic tissues.
Cytokine 49(1) , 114-21, (2010) The present study was undertaken to investigate the anti-arthritic activity of hydroxychavicol (HC) a major phenolic compound isolated from the aqueous extract leaves of plant Piper betle (Piperaceae). The compound showed significant lowering of pro-inflammat... |
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Hydroxychavicol inhibits immune responses to mitigate cognitive dysfunction in rats.
J. Neuroimmunol. 226(1-2) , 48-58, (2010) This study was carried out to investigate the protective effect of Hydroxychavicol (HC), a phenolic compound derived from Piper betel on experimentally induced Alzheimer's disease (AD) in rat. HC at graded doses administered orally once daily for a duration o... |
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In vitro antifungal activity of hydroxychavicol isolated from Piper betle L.
Ann. Clin. Microbiol. Antimicrob. 9 , 7, (2010) Hydroxychavicol, isolated from the chloroform extraction of the aqueous leaf extract of Piper betle L., (Piperaceae) was investigated for its antifungal activity against 124 strains of selected fungi. The leaves of this plant have been long in use tropical co... |
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Simultaneous estimation of hydroxychavicol and chlorogenic acid from Piper betel L. through RP-HPLC.
Nat. Prod. Res. 26(20) , 1939-41, (2012) A RP-HPLC method was developed (λ (max) =280) to quantify hydroxychavicol and chlorogenic acid in Piper betel Linn. The method was validated for linearity, limit of detection (LOD=3:1σ/S), limit of quantification (LOQ=10:1σ/S), precision, accuracy and ruggedn... |
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Inducing the cell cycle arrest and apoptosis of oral KB carcinoma cells by hydroxychavicol: roles of glutathione and reactive oxygen species.
Br. J. Pharmacol. 135(3) , 619-30, (2002) Hydroxychavicol (HC; 10 - 50 microM), a betel leaf component, was found to suppress the 2% H(2)O(2)-induced lucigenin chemiluminescence for 53 - 75%. HC (0.02 - 2 microM) was also able to trap superoxide radicals generated by a xanthine/xanthine oxidase syste... |
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Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization.
Br. J. Pharmacol. 152(1) , 73-82, (2007) Platelet hyperactivity is important in the pathogenesis of cardiovascular diseases. Betel leaf (PBL) is consumed by 200-600 million betel quid chewers in the world. Hydroxychavicol (HC), a betel leaf component, was tested for its antiplatelet effect.We tested... |