4-氯-N-甲基苯胺
4-氯-N-甲基苯胺结构式
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常用名 | 4-氯-N-甲基苯胺 | 英文名 | 4-Chloro-N-methylaniline |
|---|---|---|---|---|
| CAS号 | 932-96-7 | 分子量 | 141.598 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 240.8±13.0 °C at 760 mmHg | |
| 分子式 | C7H8ClN | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 51.7±0.0 °C | |
| 符号 |
GHS02, GHS05, GHS07 |
信号词 | Danger |
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The role of pharmacokinetics and metabolism in species sensitivity to neurotoxic agents.
Fundam. Appl. Toxicol. 6(2) , 190-207, (1986) Attempts have been made to review the role of pharmacokinetics and metabolism in species and age sensitivity as well as the development of various toxic conditions of some neurotoxic chemicals. The route of administration may play a prominent role in the deve... |
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Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists.
Bioorg. Med. Chem. Lett. 20(4) , 1363-7, (2010) A series of 3-aryl-4-isoxazolecarboxamides identified from a high-throughput screening campaign as novel, potent agonists of the human TGR5 G-protein-coupled receptor is described. Many analogues were readily accessible via solution-phase synthesis which resu... |
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FT-IR, FT-Raman, NMR spectra and DFT calculations on 4-chloro-N-methylaniline.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 75(5) , 1523-9, (2010) In this work, the vibrational spectral analysis was carried out by using FT-IR and FT-Raman spectroscopy in the range 400-4000 and 50-3500cm(-1) respectively, for the title molecule. The structural and spectroscopic data of the molecule in the ground state we... |
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Inhibition of hepatic drug metabolism in VX2 carcinoma-bearing rabbits.
Drug Metab. Dispos. 8(3) , 139-42, (1980) Hepatic metabolism of aniline, p-chloro-N-methylaniline, and aminopyrine was determined in control male, New Zealand White rabbits or those bearing VX2 carcinoma (a prostaglandin-secreting tumor). In addition, the levels of cyclic AMP and cyclic GMP in the li... |
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Effect of dietary malathion on hepatic microsomal drug-metabolizing systems of Gallus domesticus.
Toxicol. Lett. 31(2) , 107-11, (1986) White leghorn cockerels were fed a diet containing 0, 400, 800 and 1600 ppm of malathion for 90 days. Malathion O,O-dimethyl S-(1,2-dicarbethoxy) ethyl phosphorodithioate) at 800 and 1600 ppm caused a significant decrease in body weights. There was a signific... |
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Studies on the cytochrome P-450 of avocado (Persea [corrected] americana) mesocarp microsomal fraction.
Xenobiotica 20(7) , 711-26, (1990) 1. Because of the low concentration of cytochrome P-450 in avocado fruit, microsomal fractions were prepared using polyethylene glycol aggregation and low-speed centrifugation, thus avoiding the need for high-speed centrifugation of large volumes of post-mito... |
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[Acute hemorrhagic cystitis following chlordimeform poisoning ].
Dtsch. Med. Wochenschr. 116(21) , 816-8, (1991) A 19-year-old and a 50-year-old man who together had cleaned a water-tank as part of their duties in a tank protection and cleaning firm developed that same evening lower abdominal pain, dysuria and haematuria. Cystoscopy revealed haemorrhagic cystitis in bot... |
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One-pot synthesis of N-methylindoles from N-methylanilines and of benzofurans from phenols using transition-metal carbene X-H insertion reactions. Honey MA, et al.
Tetrahedron 65(44) , 8995-9001, (2009)
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