BETA-雌二醇 3-硫酸钠盐
BETA-雌二醇 3-硫酸钠盐结构式
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常用名 | BETA-雌二醇 3-硫酸钠盐 | 英文名 | 17-Beta-Estradiol-3-O-Sulfate Sodium |
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| CAS号 | 4999-79-5 | 分子量 | 374.427 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C18H23NaO5S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07, GHS08 |
信号词 | Warning |
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Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate.
J. Steroid Biochem. Mol. Biol. 96(5) , 367-74, (2005) Using recombinant sulfotransferases (SULTs) expressed in E. coli, beta-estradiol (E2) sulfonation was examined to determine which SULT enzyme is responsible for producing E2-17-sulfate (E2-17-S). SULTs 1A1*1, 1A1*2, 1A3, 1E1 and 2A1 all sulfated E2 to varying... |
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Steroid sulphate secretion by the human ovary in vitro: influence of gonadotrophins, cyclofenil and clomiphene.
J. Steroid Biochem. 13(12) , 1401-6, (1980)
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[Evidence, in vitro, of estrone and estradiol-17 beta 3-sulfoconjugate hydrolysis in the uterus of pregnant guinea pigs].
C. R. Seances. Acad. Sci. III. 292(9) , 609-12, (1981) The metabolism, in vitro, of [6,7-3H]-oestrone-3-sulfate and [6,7-3H]-oestradiol-17beta-3-sulfate by the uteri of pregnant female Guinea-Pigs has been studied using 900 g supernatants. A hydrolysis of the sulfate moiety was observed: 35% of the radioactivity ... |
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Genomics of estradiol-3-sulfate action in the ovine fetal hypothalamus.
Physiol. Genomics 44(13) , 669-77, (2012) In fetal sheep during late gestation sulfoconjugated estrogens in plasma reach a concentration 40-100 times greater than unconjugated estrogens. The objective of the present study was to determine the genomics of estradiol-3-sulfate (E(2)S) action in the ovin... |
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Fetal hypothalamus-pituitary-adrenal responses to estradiol sulfate.
Endocrinology 152(12) , 4966-73, (2011) Estradiol (E(2)) is an important modifier of the activity of the fetal hypothalamus-pituitary-adrenal axis. We have reported that estradiol-3-sulfate (E(2)SO(4)) circulates in fetal blood in far higher concentrations than E(2) and that the fetal brain express... |
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The in vitro metabolism of estrone and estradiol-17 beta and their 3-sulfates by the renal tissues from pregnant and female fetal guinea-pigs.
J. Steroid Biochem. 15 , 453-9, (1981)
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Specific antisera for the radioimmunoassay of estradiol-3-sulfate.
J. Steroid Biochem. 22(2) , 285-8, (1985) Antisera were prepared against two types of estradiol-3-sulfate-bovine serum albumin (BSA) conjugates. The haptens were coupled to BSA through the C-6 position in the steroid molecule by the glutaraldehyde (A) or the carbodiimide method (B). In comparison the... |
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Determination of estrogen 3-sulfates in biological fluids of mammary tumor-bearing rats by radioimmunoassay.
Nucl. Med. Biol. 20(4) , 493-501, (1993) Determination of estradiol 3-sulfate (E2 3-S) and estriol 3-sulfate (E3 3-S) in plasma, urine or tumor tissues of mammary tumor-bearing rats were performed using the superior radioimmunoassay (RIA) system. The plasma level of E2 3-S after tumorigenesis was fo... |
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The arrival and discharge of conjugated estrogens from a range of different sewage treatment plants in the UK.
Chemosphere 82(8) , 1124-8, (2011) The occurrence of free and conjugated estrogens was examined in a survey of eleven sewage treatment plants (STPs) and their discharge water in the United Kingdom using grab sampling. The STPs included trickling filter with and without tertiary treatment, and ... |
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Isolation and identification of intestinal steroid-desulfating bacteria from rats and humans.
Appl. Environ. Microbiol. 54(8) , 2112-7, (1988) We isolated 12 strictly anaerobic steroid-3-sulfate-desulfating strains from the intestinal floras of rats and humans. Two strains (S1 and S2) of the same atypical Clostridium species and an atypical Lactobacillus strain (termed R9) were obtained from rats. T... |