芳香法宗
芳香法宗结构式
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常用名 | 芳香法宗 | 英文名 | Famprofazone |
|---|---|---|---|---|
| CAS号 | 22881-35-2 | 分子量 | 377.52200 | |
| 密度 | 1.083g/cm3 | 沸点 | 485.1ºC at 760mmHg | |
| 分子式 | C24H31N3O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 184.8ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine.
Drug Metab. Rev. 32(1) , 15-44, (2000) The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution of urine samples and the knowledge about legitimate and il... |
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Detection and identification of famprofazone and its metabolite in human urine.
J. Chromatogr. B, Biomed. Appl. 661(2) , 255-61, (1994) Detection and identification of famprofazone and its metabolite, p-hydroxydesmethylfamprofazone, were described. The identity of the new metabolite was confirmed by comparing its mass spectrum and gas chromatographic retention time with that of the synthetic ... |
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Urinary methamphetamine concentration following famprofazone administration.
J. Anal. Toxicol. 18(5) , 265-8, (1994) A 37-year-old man had a considerable concentration of methamphetamine in his urine, but he denied taking any abused drug. It was found that he took a pain killer that contains famprofazone, a relatively strong analgesic whose metabolites include methamphetami... |
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Enantiomeric composition of amphetamine and methamphetamine derived from the precursor compound famprofazone.
Forensic Sci. Int. 80(3) , 189-99, (1996) Fourteen different metabolic precursors of amphetamine or methamphetamine have previously been identified. Many of these drugs are available only by prescription and several are only available in some parts of the world and not in others. One of these drugs, ... |
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Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results.
J. Occup. Environ. Med. 44(5) , 435-50, (2002) Medical Review Officer interpretation of laboratory results is an important component of drug testing programs. The clinical evaluation of laboratory results to assess the possibility of appropriate medical use of a drug is a task with many different facets, ... |
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Plasma and urinary concentrations of methamphetamine after oral administration of famprofazone to man.
Xenobiotica 22(3) , 377-84, (1992) 1. To obtain further evidence for the metabolic formation of methamphetamine from famprofazone in man, concentrations of methamphetamine in plasma, as well as in urine, were measured by g.l.c. In addition, intact famprofazone and famprofazone N-oxide were ana... |
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Metabolic profile of amphetamine and methamphetamine following administration of the drug famprofazone.
J. Anal. Toxicol. 27(7) , 479-84, (2003) There are a several drugs that lead to the production of methamphetamine and/or amphetamine in the body which are subsequently excreted in the urine. These drugs raise obvious concerns when interpreting positive amphetamine drug testing results. Famprofazone ... |
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Stereoselective metabolism of famprofazone in humans: N-dealkylation and beta- and p-hydroxylation.
Chirality 9(1) , 52-8, (1997) Following administration of famprofazone to humans, the stereoselective metabolism from the drug to its known metabolites (+,-)-ephedrine, (+,-)-pseudoephedrine, (+,-)-norephedrine, (+,-)-norpseudoephedrine, (+,-)-p-hyroxyamphetamine, (+,-)-p-hydroxymethamphe... |
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Identification of famprofazone ingestion.
Int. J. Legal Med. 111(6) , 305-8, (1998) After a traffic accident a 32-year-old man was suspected of having previously taken an illegal drug. An immunochemical screening procedure revealed positive results for amphetamines in both urine and blood samples. The preliminary test was confirmed by GC/MS ... |
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Identification of new urinary metabolites of famprofazone in humans.
J. Anal. Toxicol. 22(1) , 55-60, (1998) Urinary metabolites of famprofazone following oral administration in humans were identified by gas chromatography-mass spectrometry with electron impact-ionization and comparison with the spectra and retention times of authentic standards. The metabolites wer... |