ω-芋螺毒素MVIIC
ω-芋螺毒素MVIIC结构式
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常用名 | ω-芋螺毒素MVIIC | 英文名 | ω-Conotoxin MVIIC |
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| CAS号 | 147794-23-8 | 分子量 | 2749.251 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C106H178N40O32S7 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Mechanisms underlying mechanosensitivity of mesenteric afferent fibers to vascular flow.
Am. J. Physiol. Gastrointest. Liver Physiol. 293(2) , G422-8, (2007) Spinal afferent neurons, with endings in the intestinal mesenteries, have been shown to respond to changes in vascular perfusion rates. The mechanisms underlying this sensitivity were investigated in an in vitro preparation of the mesenteric fan devoid of con... |
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Glutamate regulates neurite outgrowth of cultured descending brain neurons from larval lamprey.
Dev. Neurobiol. 67(2) , 173-88, (2007) In larval lamprey, descending brain neurons, which regenerate their axons following spinal cord injury, were isolated and examined in cell culture to identify some of the factors that regulate neurite outgrowth. Focal application of 5 mM or 25 mM L-glutamate ... |
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Effects of Ca2+ channel antagonists on acetylcholine and catecholamine releases in the in vivo rat adrenal medulla.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 287(1) , R161-6, (2004) To elucidate the types of voltage-dependent Ca(2+) channels controlling ACh and catecholamine releases in the in vivo adrenal medulla, we implanted microdialysis probes in the left adrenal medulla of anesthetized rats and investigated the effects of Ca(2+) ch... |
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Activation of neuropeptide Y Y1 receptors inhibits glutamate release through reduction of voltage-dependent Ca2+ entry in the rat cerebral cortex nerve terminals: suppression of this inhibitory effect by the protein kinase C-dependent facilitatory pathway.
Neuroscience 134(3) , 987-1000, (2005) Neuropeptide Y (NPY) is known to regulate the presynaptic glutamate release and neuronal responses to excitatory neurotransmission. The aim of this study was to investigate the effect of NPY on the release of endogenous glutamate from rat cerebrocortical nerv... |
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Hyposmolarity evokes norepinephrine efflux from synaptosomes by a depolarization- and Ca2+ -dependent exocytotic mechanism.
Eur. J. Neurosci. 22(7) , 1636-42, (2005) Osmolarity reduction (20%) elicited 3H-norepinephrine (NE) efflux from rat cortical synaptosomes. The hyposmotic NE release resulted from the following events: (i) a Na+-dependent and La3+-, Gd3+- and ruthenium red-sensitive depolarization; (ii) a cytosolic C... |
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The long-term effect of toosendanin on current through nifedipine-sensitive Ca2+ channels in NG108-15 cells.
Toxicon 45(1) , 53-60, (2005) Toosendanin is a triterpenoid derivative extracted from Melia toosendan Sieb et Zucc. Previous studies demonstrated that toosendanin could block neurotransmission and stimulate PC12 cell into differentiation and apoptosis. These actions of toosendanin were su... |
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Contribution of L-type channels to Ca2+ regulation of neuronal properties in early developing purkinje neurons.
Cerebellum 4(2) , 128-39, (2005) Activity driven Ca2+ signaling is an important regulator of neuronal development. Early developing Purkinje neurons (postnatal day 5-7) prior to the stage of dendritic development express a somatic Ca2+ signaling pathway that is electrically driven and commun... |
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Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A.
Naunyn Schmiedebergs Arch. Pharmacol. 384(1) , 59-70, (2011) The present study was aimed at investigating the effect and the possible mechanism of idebenone on endogenous glutamate release in nerve terminals of rat cerebral cortex (synaptosomes). Idebenone inhibited the release of glutamate that was evoked by exposing ... |
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Calcium channel subtypes for cholinergic and nonadrenergic noncholinergic neurotransmission in isolated guinea pig trachea.
Naunyn Schmiedebergs Arch. Pharmacol. 382(5-6) , 419-32, (2010) The Ca(2+) channel subtypes in the neurotransmission of isolated guinea pig trachea were elucidated by monitoring the effects of specific Ca(2+) channel blockers on cholinergic contractions and nonadrenergic noncholinergic (NANC) relaxation elicited by electr... |
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Characteristics of omega-conotoxin GVI A and MVIIC binding to Cav 2.1 and Cav 2.2 channels captured by anti-Ca2+ channel peptide antibodies.
Neurochem. Res. 30(4) , 457-66, (2005) A New Binding Method (NBM) was used to investigate the characteristics of the specific binding of 125I-omega-conotoxin (omega-CTX) GVIA and 125I-omega-CTX MVIIC to Cav2.1 and Cav2.2 channels captured from chick brain membranes by antibodies against B1Nt (a pe... |