ω-芋螺毒素MVIIC

更新时间:2024-01-01 22:42:59

ω-芋螺毒素MVIIC结构式
ω-芋螺毒素MVIIC结构式
品牌特惠专场
常用名 ω-芋螺毒素MVIIC 英文名 ω-Conotoxin MVIIC
CAS号 147794-23-8 分子量 2749.251
密度 1.6±0.1 g/cm3 沸点 N/A
分子式 C106H178N40O32S7 熔点 N/A
MSDS 美版 闪点 N/A

 ω-芋螺毒素MVIIC用途


ω-Conotoxin MVIIC 是一种 N 和 P/Q 型钙通道 (Ca2+ channel) 阻滞剂,可显着阻断 11-keto-βboswellic acid 介导的谷氨酸释放抑制。

 ω-芋螺毒素MVIIC名称

中文名 OMEGA-芋螺毒素 M VIIC
英文名 {(1R,4S,7S,10S,13S,16S,19S,22R,27R,30S,36S,39S,45R,48S,54S,57R,62R,65S,71S,77S,83S)-62-Amino-7,30,65,71-tetrakis(4-aminobutyl)-4,36,39-tris(3-carbamimidamidopropyl)-27-carbamoyl-16-(4-hydroxybenzyl)-10-(1-hydroxyethyl)-48,54-bis(hydroxymethyl)-77-methyl-13-[2-(methylsulfanyl)ethyl]-2,5,8,11,14,17,20,29,32,35,38,41,44,47,50,53,56,63,66,69,72,75,78,84,91-pentacosaoxo-24,25,59,60,87,88-hexathia-3,6,9,12,15,18,21,28,31,34,37,40,43,46,49,52,55,6$CYS-LYS-GLY-LYS-GLY-ALA-PRO-CYS-ARG-LYS-THR-MET-TYR-ASP-CYS-CYS-SER-GLY-SER-CYS-GLY-ARG-ARG-GLY-LYS-CYS-NH2
英文别名 更多

 ω-芋螺毒素MVIIC生物活性

描述 ω-Conotoxin MVIIC 是一种 N 和 P/Q 型钙通道 (Ca2+ channel) 阻滞剂,可显着阻断 11-keto-βboswellic acid 介导的谷氨酸释放抑制。
相关类别
参考文献

[1]. Cheng Wei Lu, et al. 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus. Planta Med. 2020 Apr;86(6):434-441.

 ω-芋螺毒素MVIIC物理化学性质

密度 1.6±0.1 g/cm3
分子式 C106H178N40O32S7
分子量 2749.251
精确质量 2747.157471
PSA 1372.92000
LogP -20.33
外观性状 白色冻干的固体
折射率 1.723
储存条件 -20°C, 避光干燥

 ω-芋螺毒素MVIIC安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 UN 3172
包装等级 III
危险类别 6.1(b)

 ω-芋螺毒素MVIIC文献28

更多文献
Mechanisms underlying mechanosensitivity of mesenteric afferent fibers to vascular flow.

Am. J. Physiol. Gastrointest. Liver Physiol. 293(2) , G422-8, (2007)

Spinal afferent neurons, with endings in the intestinal mesenteries, have been shown to respond to changes in vascular perfusion rates. The mechanisms underlying this sensitivity were investigated in ...

Glutamate regulates neurite outgrowth of cultured descending brain neurons from larval lamprey.

Dev. Neurobiol. 67(2) , 173-88, (2007)

In larval lamprey, descending brain neurons, which regenerate their axons following spinal cord injury, were isolated and examined in cell culture to identify some of the factors that regulate neurite...

Effects of Ca2+ channel antagonists on acetylcholine and catecholamine releases in the in vivo rat adrenal medulla.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 287(1) , R161-6, (2004)

To elucidate the types of voltage-dependent Ca(2+) channels controlling ACh and catecholamine releases in the in vivo adrenal medulla, we implanted microdialysis probes in the left adrenal medulla of ...

 ω-芋螺毒素MVIIC英文别名

CTX MVIIC
conotoxin MVIIC
omega-Conotoxin M VIIC
{(1R,4S,7S,10S,13S,16S,19S,22R,27R,30S,36S,39S,45R,48S,54S,57R,62R,65S,71S,77S,83S)-62-Amino-7,30,65,71-tetrakis(4-aminobutyl)-4,36,39-tris(3-carbamimidamidopropyl)-27-carbamoyl-16-(4-hydroxybenzyl)-10-(1-hydroxyethyl)-48,54-bis(hydroxymethyl)-77-methyl-13-[2-(methylsulfanyl)ethyl]-2,5,8,11,14,17,20,29,32,35,38,41,44,47,50,53,56,63,66,69,72,75,78,84,91-pentacosaoxo-24,25,59,60,87,88-hexathia-3,6,9,12,15,18,21,28,31,34,37,40,43,46,49,52,55,6
Snx 230
conotoxin MVIIC_smartox
{(1R,4S,7S,13S,16S,19S,22R,27R,30S,36S,39S,45R,48S,54S,57R,62R,65S,71S,77S,83S)-62-Amino-7,30,65,71-tetrakis(4-aminobutyl)-4,36,39-tris(3-carbamimidamidopropyl)-27-carbamoyl-16-(4-hydroxybenzyl)-10-[(1R)-1-hydroxyethyl]-48,54-bis(hydroxymethyl)-77-methyl-13-[2-(methylsulfanyl)ethyl]-2,5,8,11,14,17,20,29,32,35,38,41,44,47,50,53,56,63,66,69,72,75,78,84,91-pentacosaoxo-24,25,59,60,87,88-hexathia-3,6,9,12,15,18,21,28,31,34,37,40,43,46,49,52,55,
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