1,2,3-丙烷三甲酸
1,2,3-丙烷三甲酸结构式
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常用名 | 1,2,3-丙烷三甲酸 | 英文名 | Tricarballylic acid |
|---|---|---|---|---|
| CAS号 | 99-14-9 | 分子量 | 176.124 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 266.4±20.0 °C at 760 mmHg | |
| 分子式 | C6H8O6 | 熔点 | 156-161 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 129.2±18.3 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Enhanced shRNA delivery and ABCG2 silencing by charge-reversible layered nanocarriers.
Small 11(8) , 952-62, (2015) Polycationic vectors have been used to deliver short hairpin RNAs (shRNAs) to knock-down genes for cancer therapies, but their inefficiency in lysosomal escape and shRNA release causes their low gene transcription efficiency. Herein, a three-layered polyethyl... |
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Citrate modulates lipopolysaccharide-induced monocyte inflammatory responses.
Clin. Exp. Immunol. 180 , 520-30, (2015) Citrate, a central component of cellular metabolism, is a widely used anti-coagulant due to its ability to chelate calcium. Adenosine triphosphate (ATP)-citrate lyase, which metabolizes citrate, has been shown to be essential for inflammation, but the ability... |
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Reactions of atomic metal anions in the gas phase: competition between electron transfer, proton abstraction and bond activation.
J. Phys. Chem. A 115(48) , 14006-12, (2011) Bare metal anions K(-), Rb(-), Cs(-), Fe(-), Co(-), Ni(-), Cu(-), and Ag(-), generated by electrospray ionization of the corresponding oxalate or tricarballylate solutions, were allowed to react with methyl and ethyl chloride, methyl bromide, nitromethane, an... |
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The Tricarballylate utilization (tcuRABC) genes of Salmonella enterica serovar Typhimurium LT2.
J. Bacteriol. 186(6) , 1629-37, (2004) The genes of Salmonella enterica serovar Typhimurium LT2 encoding functions needed for the utilization of tricarballylate as a carbon and energy source were identified and their locations in the chromosome were established. Three of the tricarballylate utiliz... |
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Combined synthetic/CD strategy for the stereochemical assignment of the tricarballylic acid side chains of fumonisin B(1).
J. Org. Chem. 66(11) , 3678-81, (2001) The circular dichroism (CD) exciton chirality method was employed for the stereochemical assignment of the tricarballylic acid (TCA) side chains of fumonisin B(1) 1a (FB(1)). Using 2-naphthoate for chromophoric derivatization of the reduced TCA moieties, the ... |
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Tricarballylate catabolism in Salmonella enterica. The TcuB protein uses 4Fe-4S clusters and heme to transfer electrons from FADH2 in the tricarballylate dehydrogenase (TcuA) enzyme to electron acceptors in the cell membrane.
Biochemistry 46(31) , 9107-15, (2007) Tricarballylate, a citrate analogue, is considered the causative agent of grass tetany, a ruminant disease characterized by acute magnesium deficiency. Although the normal rumen flora cannot catabolize tricarballylate, the Gram-negative enterobacterium Salmon... |
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Perturbations in hypoxia detection: a shared link between hereditary and sporadic tumor formation?
Med. Hypotheses 66(4) , 732-5, (2006) The discovery and characterization of the von Hippel Lindau (VHL) syndrome has brought about tremendous advances in understanding the molecular mechanisms of renal cell carcinoma. VHL mutations are known to act through hypoxia inducible factor, which has a ph... |
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Regulation of expression of the tricarballylate utilization operon (tcuABC) of Salmonella enterica.
Res. Microbiol. 160(3) , 179-86, (2009) The tricarballylate utilization locus (tcuRABC) of Salmonella enterica serovar Typhimurium is comprised of a 3-gene operon (tcuABC) that encodes functions that allow this bacterium to use tricarballylate as a source of carbon and energy, and the tcuR gene, wh... |
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Effect of fat substitutes, sucrose polyester and tricarballylate triester, on digitoxin absorption in the rat.
J. Pharm. Pharmacol. 45(8) , 692-6, (1993) The effect of non-absorbable fat substitutes (sucrose polyester (SPE) and tricarballylate triester (TCTE)) on [3H]digitoxin intestinal absorption was studied in the rat using a small intestine in-situ perfusion technique. The effect of SPE and TCTE was compar... |
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Involvement of the Cra global regulatory protein in the expression of the iscRSUA operon, revealed during studies of tricarballylate catabolism in Salmonella enterica.
J. Bacteriol. 191(7) , 2069-76, (2009) In Salmonella enterica, tricarballylate (Tcb) catabolism requires function of TcuB, a membrane-bound protein that contains [4Fe-4S] clusters and heme. TcuB transfers electrons from reduced flavin adenine dinucleotide in the Tcb dehydrogenase (TcuA) to electro... |