溴鼠灵
一般危化品
溴鼠灵结构式
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常用名 | 溴鼠灵 | 英文名 | Brodifacoum |
|---|---|---|---|---|
| CAS号 | 56073-10-0 | 分子量 | 523.417 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 679.0±55.0 °C at 760 mmHg | |
| 分子式 | C31H23BrO3 | 熔点 | 228-230ºC | |
| MSDS | 中文版 美版 | 闪点 | 364.4±31.5 °C | |
| 符号 |
GHS06, GHS08, GHS09 |
信号词 | Danger |
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Notable pink excreta and severe myocardial suppression in superwarfarin (difethialone) intoxication.
Intern. Med. 50(22) , 2819-22, (2011) Patients rarely consult physicians before developing coagulopathy or bleeding in most reported cases of superwarfarin intoxication. A 57-year-old woman ingested red-dyed pellets of anticoagulant rodenticide containing difethialone and warfarin as well as tabl... |
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Symptomatic brodifacoum ingestion requiring high-dose phytonadione therapy.
Vet. Hum. Toxicol. 36(3) , 216-7, (1994) We report the deliberate ingestion of a superwarfarin product, brodifacoum, in a 39-y-old male. He presented with prothrombin and partial thromboplastin times of 150 and 113 sec, respectively. His coagulopathy was corrected by administration of blood products... |
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Does small mammal prey guild affect the exposure of predators to anticoagulant rodenticides?
Environ. Pollut. 159(10) , 3106-12, (2011) Ireland has a restricted small mammal prey guild but still includes species most likely to consume anticoagulant rodenticide (AR) baits. This may enhance secondary exposure of predators to ARs. We compared liver AR residues in foxes (Vulpes vulpes) in Norther... |
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Determination of bromadiolone and brodifacoum in human hair by liquid chromatography/tandem mass spectrometry and its application to poisoning cases.
Rapid Commun. Mass Spectrom. 27(4) , 513-20, (2013) Bromadiolone and brodifacoum, two common anticoagulant rodenticides, are involved in the majority of anticoagulant rodenticide poisoning cases in humans in China. Hair analysis can provide long-term information on drug exposure. A method using liquid chromato... |
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Second generation anticoagulant rodenticides in predatory birds: Probabilistic characterisation of toxic liver concentrations and implications for predatory bird populations in Canada
Environ. Int. 37(5) , 914-20, (2011) Second-generation anticoagulant rodenticides (SGARs) are widely used to control rodent pests but exposure and poisonings occur in non-target species, such as birds of prey. Liver residues are often analysed to detect exposure in birds found dead but their use... |
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High exposure rates of anticoagulant rodenticides in predatory bird species in intensively managed landscapes in Denmark.
Arch. Environ. Contam. Toxicol. 63(3) , 437-44, (2012) The extensive use of anticoagulant rodenticides (ARs) for rodent control has led to widespread secondary exposure in nontarget predatory wildlife species. We investigated exposure rates and concentrations of five ARs in liver samples from five raptors and six... |
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Determination of bromadiolone and brodifacoum in human blood using LC-ESI/MS/MS and its application in four superwarfarin poisoning cases.
Forensic Sci. Int. 222(1-3) , 313-7, (2012) Superwarfarin poisoning is a growing health problem. A sensitive and reproducible LC-ESI/MS/MS (liquid chromatography electrospray ionization tandem mass spectrometry) method was developed and validated for the determination of bromadiolone and brodifacoum, t... |
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Upper gastrointestinal hemorrhage caused by superwarfarin poisoning.
World J. Gastroenterol. 16(13) , 1680-2, (2010) Superwarfarins are a class of rodenticides. Gastrointestinal hemorrhage is a fatal complication of superwarfarin poisoning, requiring immediate treatment. Here, we report a 55-year-old woman with tardive upper gastrointestinal hemorrhage caused by superwarfar... |
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Practical synthesis of hydroxychromenes and evaluation of their biological activity.
Molecules 17(1) , 240-7, (2011) A simple and efficient seven steps synthesis of brodifacoum and difethialone from phenylacetyl chloride is described. The key synthetic strategies involve Friedel-Crafts acylation, intramolecular ring cyclization and condensation reaction in the presence of B... |
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Korean patients with superwarfarin intoxication and their outcome.
J. Korean Med. Sci. 25(12) , 1754-8, (2010) This observational study aimed at evaluating recent superwarfarin intoxication of Korean patients. Ten patients were diagnosed as or highly suspicious for superwarfarin intoxication. Case report forms described by attending hematologists of the patients were ... |