2'-脱氧鸟苷一水合物
2'-脱氧鸟苷一水合物结构式
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常用名 | 2'-脱氧鸟苷一水合物 | 英文名 | 2'-Deoxyguanosine monohydrate |
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| CAS号 | 312693-72-4 | 分子量 | 267.24100 | |
| 密度 | N/A | 沸点 | 801.4ºC at 760 mmHg | |
| 分子式 | C10H13N5O4 | 熔点 | 300ºC | |
| MSDS | 中文版 美版 | 闪点 | 438.5ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Induction of ROS generation by fluconazole in Candida glabrata: activation of antioxidant enzymes and oxidative DNA damage.
Diagn. Microbiol. Infect. Dis. 82 , 203-8, (2015) In this study, we assessed the generation of reactive oxygen species (ROS) induced by subinhibitory concentration of fluconazole in susceptible and resistant Candida glabrata strains at stationary growth phase and measured their oxidative responses parameters... |
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Copper/H2O2-mediated oxidation of 2'-deoxyguanosine in the presence of 2-naphthol leads to the formation of two distinct isomeric adducts.
J. Org. Chem. 76(19) , 7953-63, (2011) Exposure of cells to phenolic compounds through exogenous and endogenous sources can lead to deleterious effects via nucleobase modifications of DNA occurring under oxidative conditions. 2'-Deoxyguanosine (dG) is the most electron rich of the four canonical b... |
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Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker in type 2 diabetes.
Free Radic. Biol. Med. 51(8) , 1473-9, (2011) The increasing prevalence of diabetes together with the associated morbidity and mortality calls for additional preventive and therapeutic strategies. New biomarkers that can be used in therapy control and risk stratification as alternatives to current method... |
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Characterization of DNA with an 8-oxoguanine modification.
Nucleic Acids Res. 39 , 6789-7801, (2011) The oxidation of DNA resulting from reactive oxygen species generated during aerobic respiration is a major cause of genetic damage that, if not repaired, can lead to mutations and potentially an increase in the incidence of cancer and aging. A major oxidatio... |
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Lipid hydroperoxide-induced and hemoglobin-enhanced oxidative damage to colon cancer cells
Free Radic. Biol. Med. 51 , 503-515, (2011) Epidemiological studies have indicated that Western diets are related to an increase in a series of malignancies. Among the compounds that are credited for this toxic effect are heme and lipid peroxides. We evaluated the effects of hemoglobin (Hb) and linolei... |
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BODIPY-modified 2'-deoxyguanosine as a novel tool to detect DNA damages.
Bioorg. Med. Chem. Lett. 21 , 4206-4209, (2011) BODIPY-modified 2'-deoxyguanosine was synthesized for use as a detection reagent for genotoxic compounds. BODIPY-FL is a well known fluorescence reagent whose fluorescent light emission diminishes near a guanine base by a photo-induced electron transfer proce... |