[His(π-Methyl)2]-LH-RH
![[His(π-Methyl)2]-LH-RH结构式](https://image.chemsrc.com/caspic/373/38343-58-7.png)
[His(π-Methyl)2]-LH-RH结构式
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常用名 | [His(π-Methyl)2]-LH-RH | 英文名 | (His(3-Me)2)-LHRH trifluoroacetate salt |
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| CAS号 | 38343-58-7 | 分子量 | 1196.32000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C56H77N17O13 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
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Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse.
PLoS Biol. 12(9) , e1001952, (2014) Characterization of the genetic defects causing gonadotropic deficiency has made a major contribution to elucidation of the fundamental role of Kisspeptins and Neurokinin B in puberty onset and reproduction. The absence of puberty may also reveal neurodevelop... |
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R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism.
PLoS ONE 8(7) , e69616, (2013) Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of autosomal recessive nCHH. R31C GNRH1 is the only missense mu... |
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Characterization of 12 GnRH peptide agonists - a kinetic perspective.
Br. J. Pharmacol. 173(1) , 128-41, (2016) Drug-target residence time is an important, yet often overlooked, parameter in drug discovery. Multiple studies have proposed an increased residence time to be beneficial for improved drug efficacy and/or longer duration of action. Currently, there are many d... |