(His(3-Me)2)-LHRH trifluoroacetate salt
(His(3-Me)2)-LHRH trifluoroacetate salt structure
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Common Name | (His(3-Me)2)-LHRH trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 38343-58-7 | Molecular Weight | 1196.32000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C56H77N17O13 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
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Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse.
PLoS Biol. 12(9) , e1001952, (2014) Characterization of the genetic defects causing gonadotropic deficiency has made a major contribution to elucidation of the fundamental role of Kisspeptins and Neurokinin B in puberty onset and reproduction. The absence of puberty may also reveal neurodevelop... |
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R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism.
PLoS ONE 8(7) , e69616, (2013) Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of autosomal recessive nCHH. R31C GNRH1 is the only missense mu... |
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Characterization of 12 GnRH peptide agonists - a kinetic perspective.
Br. J. Pharmacol. 173(1) , 128-41, (2016) Drug-target residence time is an important, yet often overlooked, parameter in drug discovery. Multiple studies have proposed an increased residence time to be beneficial for improved drug efficacy and/or longer duration of action. Currently, there are many d... |