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4-氟三氟甲苯

4-氟三氟甲苯结构式
4-氟三氟甲苯结构式
品牌特惠专场
常用名 4-氟三氟甲苯 英文名 p-Fluorobenzotrifluoride
CAS号 402-44-8 分子量 164.100
密度 1.3±0.1 g/cm3 沸点 104.4±35.0 °C at 760 mmHg
分子式 C7H4F4 熔点 −42-−41.7 °C(lit.)
MSDS 中文版 美版 闪点 10.6±0.0 °C
符号 GHS02 GHS07
GHS02, GHS07
信号词 Danger

Synthesis of novel trifluoromethyl-bearing bifunctional acyl-acceptant arenes: 2,2'-bis(trifluoromethylated aryloxy)biphenyls.

J. Oleo Sci. 56(9) , 479-91, (2007)

Novel bifunctional acyl-acceptant biphenyls bearing trifluoromethylated aroyloxy groups were successfully synthesized in high yields via TfOH-mediated electrophilic aromatic aroylation of fluorobenzene with CF(3)-bearing aroyl chlorides followed by nucleophil...

Absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor.

J. Med. Chem. 31(7) , 1412-7, (1988)

Fluoxetine is a potent and selective inhibitor of the neuronal serotonin-uptake carrier and is a clinically effective antidepressant. Although fluoxetine is used therapeutically as the racemate, there appears to be a small but demonstrable stereospecificity a...

Synthesis and appetite suppressant activity of 1-aryloxy-2-substituted aminomethyltetrahydronaphthalenes as conformationally rigid analogues of fluoxetine.

Bioorg. Med. Chem. 14(8) , 2535-44, (2006)

Several 1-aryloxy-2-substituted aminomethyltetrahydronaphthalenes (7-21) as conformationally rigid analogues of fluoxetine were synthesized and evaluated for their anorexigenic and antidepressant activities. For SAR studies the related acyclic analogues (22-2...