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酒石酸肾上腺素

酒石酸肾上腺素结构式
酒石酸肾上腺素结构式
品牌特惠专场
常用名 酒石酸肾上腺素 英文名 Epinephrine bitartrate
CAS号 51-42-3 分子量 333.291
密度 N/A 沸点 413.1ºC at 760 mmHg
分子式 C13H19NO9 熔点 ~155 °C (dec.)
MSDS 中文版 美版 闪点 207.9ºC
符号 GHS06
GHS06
信号词 Danger

An artificial neural network for membrane-bound catechol-O-methyltransferase biosynthesis with Pichia pastoris methanol-induced cultures.

Microb. Cell Fact. 14 , 113, (2015)

Membrane proteins are important drug targets in many human diseases and gathering structural information regarding these proteins encourages the pharmaceutical industry to develop new molecules using structure-based drug design studies. Specifically, membrane...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279...

Anthocyanins suppress the secretion of proinflammatory mediators and oxidative stress, and restore ion pump activities in demyelination.

J. Nutr. Biochem. 26(4) , 378-90, (2015)

The aim of this study was to investigate the protective effect of anthocyanins (ANT) on oxidative and inflammatory parameters, as well as ion pump activities, in the pons of rats experimentally demyelinated with ethidium bromide (EB). Rats were divided in six...

Epinephrine-stimulated glycogen breakdown activates glycogen synthase and increases insulin-stimulated glucose uptake in epitrochlearis muscles.

Am. J. Physiol. Endocrinol. Metab. 308(3) , E231-40, (2015)

Epinephrine increases glycogen synthase (GS) phosphorylation and decreases GS activity but also stimulates glycogen breakdown, and low glycogen content normally activates GS. To test the hypothesis that glycogen content directly regulates GS phosphorylation, ...

Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation.

Cell. Reprogram. 17 , 170-80, (2015)

In mice, inhibition of both the fibroblast growth factor (FGF) mitogen-activated protein kinase kinase/extracellular-signal regulated kinase (MEK/Erk) and the Wnt signaling inhibitor glycogen synthase-3β (GSK3β) enables the derivation of mouse embryonic stem ...

Masking the bitter taste of injectable lidocaine HCl formulation for dental procedures.

AAPS PharmSciTech 16(2) , 455-65, (2015)

Several attempts have been made to mask the bitter taste of oral formulations, but none have been made for injectable formulations. This study aims to mask the bitter taste of dental lidocaine HCl (LID) injection using hydroxypropyl-β-cyclodextrin (HP-β-CD) a...

Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processes.

Hum. Mol. Genet. 19 , 657-70, (2010)

Mutations in the human RPGR gene cause one of the most common and severe forms of inherited retinal dystrophy, but the function of its protein product remains unclear. We have identified two genes resembling human RPGR (ZFRPGR1, ZFRPGR2) in zebrafish (Danio r...

The N-terminal region of centrosomal protein 290 (CEP290) restores vision in a zebrafish model of human blindness.

Hum. Mol. Genet. 20 , 1467-77, (2011)

The gene coding for centrosomal protein 290 (CEP290), a large multidomain protein, is the most frequently mutated gene underlying the non-syndromic blinding disorder Leber's congenital amaurosis (LCA). CEP290 has also been implicated in several cilia-related ...

Identification and functional analysis of the vision-specific BBS3 (ARL6) long isoform.

PLoS Genet. 6 , e1000884, (2010)

Bardet-Biedl Syndrome (BBS) is a heterogeneous syndromic form of retinal degeneration. We have identified a novel transcript of a known BBS gene, BBS3 (ARL6), which includes an additional exon. This transcript, BBS3L, is evolutionally conserved and is express...