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4-溴-2-呋喃甲醛

4-溴-2-呋喃甲醛结构式
4-溴-2-呋喃甲醛结构式
品牌特惠专场
常用名 4-溴-2-呋喃甲醛 英文名 4-Bromo-2-furaldehyde
CAS号 21921-76-6 分子量 174.980
密度 1.7±0.1 g/cm3 沸点 225.0±20.0 °C at 760 mmHg
分子式 C5H3BrO2 熔点 54-58 °C
MSDS 中文版 美版 闪点 89.9±21.8 °C
符号 GHS07
GHS07
信号词 Warning

C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists.

Bioorg. Med. Chem. Lett. 17 , 3778, (2007)

A novel series of cyclobutenedione centered C(4)-alkyl substituted furanyl analogs was developed as potent CXCR2 and CXCR1 antagonists. Compound 16 exhibits potent inhibitory activities against IL-8 binding to the receptors (CXCR2 Ki=1 nM, IC(50)=1.3 nM; CXCR...