替苯丙胺
一般危化品
替苯丙胺结构式
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常用名 | 替苯丙胺 | 英文名 | 1-(1,3-benzodioxol-5-yl)propan-2-amine |
|---|---|---|---|---|
| CAS号 | 4764-17-4 | 分子量 | 179.21600 | |
| 密度 | 1.163 g/cm3 | 沸点 | 281.7ºC at 760mmHg | |
| 分子式 | C10H13NO2 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 134.9ºC | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
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Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse.
Neurotoxicology 35 , 23-9, (2013) Yearly, exposure to drugs of abuse results in ∼1 million emergency department visits in the US. In ∼50% of the visits, stimulant drugs like cocaine and amphetamine-like substances (e.g. 3,4-methylenedioxymethamphetamine (MDMA, the main active ingredient of ec... |
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Simultaneous determination of HFBA-derivatized amphetamines and ketamines in urine by gas chromatography-mass spectrometry.
J. Anal. Toxicol. 35(3) , 162-9, (2011) To facilitate the analysis of targeted drugs under high sample volume testing environment, an extraction, derivatization and gas chromatographic-mass spectrometric analysis method was developed for simultaneously determination of amphetamine (AMP), methamphet... |
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Urinary excretion profiles of N-hydroxy-3,4-methylenedioxymethamphetamine in rats.
Xenobiotica 41(7) , 578-84, (2011) N-hydroxy-3,4-methylenedioxymethamphetamine (N-OH-MDMA) is a psychedelic illicit drug that has recently been circulating in Japan. The aims of this study were (i) to optimise enzymatic hydrolysis conditions of the conjugated forms of N-OH-MDMA and its demethy... |
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"Legal highs"--toxicity in the clinical and medico-legal aspect as exemplified by suicide with bk-MBDB administration.
Forensic Sci. Int. 222(1-3) , e1-6, (2012) The easily available "legal highs", which are products containing psychoactive substances, such as cathinones, piperazines and synthetic cannabinoids, are abused by adolescents in Poland and in the world as alternatives to classic drugs, such as amphetamines ... |
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5-Iodo-2-aminoindan (5-IAI): chemistry, pharmacology, and toxicology of a research chemical producing MDMA-like effects.
Toxicol. Lett. 218(1) , 24-9, (2013) In 2010, an internet snapshot of EMCDDA anticipated the presence of 5-iodo-2-aminoindan (5-IAI) within the recreational drug market. In 2011, this compound, a psychoactive derivative of 2-aminoindane, was identified in recreational products sold in the United... |
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Simultaneous enantiomeric determination of MDMA and its phase I and phase II metabolites in urine by liquid chromatography-tandem mass spectrometry with chiral derivatization.
Anal. Bioanal. Chem 404(8) , 2427-35, (2012) A liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) procedure was developed for the simultaneous determination of enantiomers of the prevalent designer drug 3,4-methylenedioxymethamphetamine (MDMA) and its phase I and phase... |
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Effects of MDMA (ecstasy) and two of its metabolites on rat embryos in vitro.
Reprod. Toxicol. 34(1) , 57-65, (2012) MDMA consumers are young people of childbearing age. Consequently, developmental exposure to this drug is a potential public health concern. Several studies have addressed MDMA neurotoxicity in adults; however, knowledge of the effects of MDMA on developing e... |
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Investigations on the stereoselectivity of the phase II metabolism of the 3,4-methylenedioxyethylamphetamine (MDEA) metabolites 3,4-dihydroxyethylamphetamine (DHEA) and 4-hydroxy-3-methoxyethylamphetamine (HMEA).
Toxicol. Lett. 212(1) , 38-47, (2012) Different elimination was reported for the two enantiomers of the designer drug 3,4-methylenedioxyethylamphetamine (MDEA) in vivo. In the present work, the enantioselectivity of glucuronidation and sulfation of the MDEA phase I metabolites 3,4-dihydroxyethyla... |
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Molecularly imprinted solid-phase extraction for the selective determination of methamphetamine, amphetamine, and methylenedioxyphenylalkylamine designer drugs in human whole blood by gas chromatography-mass spectrometry.
J. Sep. Sci. 35(5-6) , 726-33, (2012) A novel method is described for the extraction of methamphetamine, amphetamine, and methylenedioxyphenylalkylamine designer drugs, such as 3,4-methylenedioxy-methamphetamine, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxyethylamphetamine, N-methyl-1-(3,4-m... |
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Determination of piperphentonamine and metabolites M1 and M6 in human plasma and urine by LC/MS/MS and its application in a pharmacokinetics study in Chinese healthy volunteers.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 908 , 87-93, (2012) Piperphentonamine hydrochloride (PPTA) is a new calcium sensitizer. A liquid chromatography-tandem mass spectrometry (LC/MS/MS) method for determination of piperphentonamine and its metabolites M1 and M6 was developed for the first time and applied to a pharm... |