1-甲基尿嘧啶
1-甲基尿嘧啶结构式
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常用名 | 1-甲基尿嘧啶 | 英文名 | methyluracil |
|---|---|---|---|---|
| CAS号 | 615-77-0 | 分子量 | 126.113 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 260.1ºC at 760 mmHg | |
| 分子式 | C5H6N2O2 | 熔点 | 236-238ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 111.1ºC | |
| 符号 |
GHS08 |
信号词 | Warning |
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Orotic acid decarboxylation in water and nonpolar solvents: a potential role for desolvation in the action of OMP decarboxylase.
Biochemistry 48(36) , 8738-45, (2009) OMP decarboxylase (ODCase) generates a very large rate enhancement without the assistance of metals or other cofactors. The uncatalyzed decarboxylation of 1-methylorotate in water is shown to involve the monoanion, although uncharged 1-methylorotic acid is de... |
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Thermodynamic, kinetic and structural studies on the ternary palladium(II) complexes of thioether ligands.
J. Inorg. Biochem. 79(1-4) , 129-38, (2000) Potentiometric, calorimetric, NMR and stopped-flow kinetic studies were performed on the palladium(II) complexes of thioether and/or nitrogen donor ligands. The ternary systems always contained a tridentate ligand (dien, terpy and dianions of dipeptides, GlyG... |
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Theoretical and spectroscopic study of infrared spectra of hydrogen-bonded 1-methyluracil crystal and its deuterated derivative.
J. Chem. Phys. 128(16) , 164506, (2008) Theoretical simulation of the band shape and fine structure of the N-H(D) stretching band is presented for 1-methyluracil and its deuterated derivative taking into account anharmonic coupling between the high-frequency N-H(D) stretching and the low-frequency ... |
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Pulse radiolytic studies of radicals produced from methylated uracils via oxidation by SO4..
Radiat. Res. 114(2) , 207-14, (1988) Using a pulse radiolysis technique, some nucleic base radicals were produced by the reactions of sulfate radical, SO4-, with 1-, 3-, 5-, and 6-methyluracils, and their optical and kinetic natures were observed. All of their absorption spectra showed main peak... |
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Assessment of hepatic tissue blood flow with 133Xe clearance technique.
Int. J. Nucl. Med. Biol. 8(1) , 77-84, (1981) An experimental study of the local hepatic tissue blood flow was performed with the 133Xe clearance technique on 298 anesthetized mongrel male rats and dogs. We simulated acute arterial ischemia of the liver, toxic hepatic poisoning (carbon tetrachloride pois... |
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Modeling of reaction steps relevant to deoxyuridylate (dUMP) enzymatic methylation and thymidylate synthase mechanism-based inhibition.
J. Biomol. Struct. Dyn. 15(4) , 703-15, (1998) Theoretical quantum mechanical ab initio Hartree-Fock calculations on molecular systems, modeling processes related to the specificity of thymidylate synthase inactivation are reported. We considered several steps of the methylation of the substrate dUMP and ... |
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Experimental and theoretical study of energetics of complex formation between nucleic acid bases and the bases with amide group.
J. Biomol. Struct. Dyn. 9(1) , 101-11, (1991) A number of nucleic acid base pairs and complexes between the bases and the amide group of acrylamide have been studied experimentally by using mass spectrometry and theoretically by the method of atom-atom potential function calculations. It has been found f... |
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Interplay of experiment and theory: determination of an accurate equilibrium structure of 1-methyluracil by the gas electron diffraction method and coupled-cluster computations.
J. Phys. Chem. A 117(44) , 11374-81, (2013) As far as fundamental knowledge is concerned, the methyl derivatives of uracil can be considered as the simplest objects for studying the structural effects due to the substitution in the pyrimidyne nucleobases. From this point of view, 1-methyluracil is of s... |
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Simulating the interaction between amino acids and DNA: a combined matrix-isolation FT-IR and theoretical study of the 1-methyluracil·glycine H-bond complexes using a dual sublimation furnace.
J. Phys. Chem. B 116(39) , 11890-8, (2012) The H-bond complex formation between 1-methyluracil and glycine has been investigated by theoretical calculations and the most stable complex configurations have been identified by FT-IR spectroscopy in Ar matrices. The importance of this H-bonding system is ... |
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Base-pairing configurations between purines and pyrimidines in the solid state. V. Crystal and molecular structure of two 1:1 hydrogen-bonded complexes, 1-methyluracil: 9-ethyl-8-bromo-2,6-diaminopurine and 1-ethylthymine: 9-ethyl-8-bromo-2,6--diaminopurine.
J. Mol. Biol. 48(2) , 263-78, (1970)
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