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2-溴-N-[(3S)-四氢-2-氧代-3-呋喃基]-苯乙酰胺

2-溴-N-[(3S)-四氢-2-氧代-3-呋喃基]-苯乙酰胺结构式
2-溴-N-[(3S)-四氢-2-氧代-3-呋喃基]-苯乙酰胺结构式
品牌特惠专场
常用名 2-溴-N-[(3S)-四氢-2-氧代-3-呋喃基]-苯乙酰胺 英文名 2-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide
CAS号 942296-18-6 分子量 298.13
密度 N/A 沸点 N/A
分子式 C12H12BrNO3 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones.

ACS Chem. Biol. 7(10) , 1719-28, (2012)

Many bacterial pathogens use quorum sensing (QS) to control virulence. As a result, the development of methods to intercept QS has attracted significant interest as a potential anti-infective therapy. Acinetobacter baumannii has emerged as a pan-drug-resistan...

Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones.

ChemBioChem. 12(6) , 942-9, (2011)

Bacteria can coordinate group behavior using chemical signals in a process called quorum sensing (QS). The QS system in the opportunistic pathogen Pseudomonas aeruginosa is largely governed by the LasR receptor and its cognate chemical signal, N-(3-oxo)-dodec...

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria.

Chem. Soc. Rev. 37(7) , 1432-47, (2008)

Bacteria are capable of "communicating" their local population densities via a process termed quorum sensing (QS). Gram-negative bacteria use N-acylated l-homoserine lactones (AHLs), in conjunction with their cognate LuxR-type receptors, as their primary sign...

Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa.

Bioorg. Med. Chem. Lett. 18 , 3072-5, (2008)

The transcription factor QscR is a regulator of quorum sensing in Pseudomonas aeruginosa and plays a role in controlling virulence in this prevalent opportunistic pathogen. This study outlines the discovery of a set of synthetic N-acylated homoserine lactones...