降冰片烯-2,3-二羧酸
降冰片烯-2,3-二羧酸结构式
|
常用名 | 降冰片烯-2,3-二羧酸 | 英文名 | 5-norbornene-endo-3-exo-dicarboxylic acid |
|---|---|---|---|---|
| CAS号 | 1200-88-0 | 分子量 | 182.17300 | |
| 密度 | 1.481 g/cm3 | 沸点 | 419.8ºC at 760 mmHg | |
| 分子式 | C9H10O4 | 熔点 | 185-189°C | |
| MSDS | 中文版 美版 | 闪点 | 221.8ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Propranolol targets the contractility of infantile haemangioma-derived pericytes.
Br. J. Dermatol. 171(5) , 1129-37, (2014) Propranolol, a β-adrenergic receptor (AR) antagonist, is an effective treatment for endangering infantile haemangioma (IH). Dramatic fading of cutaneous colour is often seen a short time after initiating propranolol therapy, with accelerated regression of IH ... |
|
|
Multimodal perineural analgesia with combined bupivacaine-clonidine-buprenorphine-dexamethasone: safe in vivo and chemically compatible in solution.
Pain Med. 16(1) , 186-98, (2015) The use of adjuvants in regional anesthesia has increased. However, there are knowledge gaps pertaining to 1) in vivo local tissue effects of these adjuvants; and 2) chemical compatibility and solubility of these drugs in solution with each other and with loc... |
|
|
The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism.
J. Neuroinflammation 11 , 175, (2014) The p38α mitogen-activated protein kinase (MAPK) is a well-characterized intracellular kinase involved in the overproduction of proinflammatory cytokines from glia. As such, p38α appears to be a promising therapeutic target for neurodegenerative diseases asso... |
|
|
In vitro solubility, dissolution and permeability studies combined with semi-mechanistic modeling to investigate the intestinal absorption of desvenlafaxine from an immediate- and extended release formulation.
Eur. J. Pharm. Sci. 77 , 303-13, (2015) Desvenlafaxine is a biopharmaceutics classification system (BCS) class 1 (high solubility, high permeability) and biopharmaceutical drug disposition classification system (BDDCS) class 3, (high solubility, poor metabolism; implying low permeability) compound.... |
|
|
Quantitative activation suppression assay to evaluate human bone marrow-derived mesenchymal stromal cell potency.
Cytotherapy 17 , 1675-86, (2015) With the increasing use of cell therapies involving immune modulatory cells, there is a need for a simple standardized method to evaluate and compare the suppressive potency of different cell products. We used the Karpas 299 (K299) cell line as the reference ... |
|
|
Chlorogenic acid/chromium supplement rescues diet-induced insulin resistance and obesity in mice.
Nutr. Metab. 12 , 19, (2015) Abdominal obesity is a major risk factor for insulin resistance, type 2 diabetes and cardiovascular diseases. Dietary fat induces insulin resistance in humans and rodents. The current study investigates whether a Chlorogenic acid/Chromium III supplement rescu... |
|
|
A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach.
Stem Cells Transl. Med. 4(4) , 320-32, (2015) Reprogramming human adult blood mononuclear cells (MNCs) cells by transient plasmid expression is becoming increasingly popular as an attractive method for generating induced pluripotent stem (iPS) cells without the genomic alteration caused by genome-inserti... |
|
|
Left Atrial Appendage Closure as an Alternative to Warfarin for Stroke Prevention in Atrial Fibrillation: A Patient-Level Meta-Analysis.
J. Am. Coll. Cardiol. 65 , 2614-23, (2015) The risk-benefit ratio of left atrial appendage closure (LAAC) versus systemic therapy (warfarin) for prevention of stroke, systemic embolism, and cardiovascular death in nonvalvular atrial fibrillation (NVAF) requires continued evaluation.This study sought t... |
|
|
The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination.
J. Lipid Res. 56(4) , 810-20, (2015) Previous studies suggest an interdependent relationship between liver and intestine for cholesterol elimination from the body. We hypothesized that a combination of ursodiol (Urso) and ezetimibe (EZ) could increase biliary secretion and reduce cholesterol rea... |
|
|
Breath biomarkers of whole-body gamma irradiation in the Göttingen minipig.
Health Phys. 108(5) , 538-46, (2015) There is widespread interest in the development of tools to estimate radiation exposures. Exhaled breath provides a novel matrix for assessing biomarkers that could be correlated with exposures. The use of exhaled breath for estimating radiation exposure is w... |