烟酰胺鸟嘌呤二核苷酸 钠盐
烟酰胺鸟嘌呤二核苷酸 钠盐结构式
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常用名 | 烟酰胺鸟嘌呤二核苷酸 钠盐 | 英文名 | nicotinamide guanine dinucleotide sodium salt |
|---|---|---|---|---|
| CAS号 | 5624-35-1 | 分子量 | 679.42 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C21H27N7O15P2 | 熔点 | N/A | |
| MSDS | 中文版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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ADP-ribosyl cyclase and GDP-ribosyl cyclase activities are not always equivalent: impact on the study of the physiological role of cyclic ADP-ribose.
Anal. Biochem. 346(2) , 336-8, (2005)
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Localization of the cyclic ADP-ribose-dependent calcium signaling pathway in bovine rod outer segments.
Invest. Ophthalmol. Vis. Sci. 48 , 978-984, (2007) Calcium ions play a pivotal role in phototransduction. In this study, the presence and functional role of the adenosine diphosphoribosyl (ADPR)-cyclase-cyclic ADP-ribose (cADPR) system in bovine retinal rod outer segments (ROS) was investigated.A Ca(2+) relea... |
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Purification and partial characterization of a novel phosphodiesterase from the venom of Trimeresurus stejnegeri: inhibition of platelet aggregation.
Biochimie 93 , 1601-1619, (2011) The phosphodiesterases (PDEs) are a superfamily of enzymes that have multiple roles in extracellular nucleotide metabolism and in the regulation of nucleotide-based intercellular signaling. Here we describe for the first time the isolation and partial charact... |
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Catalytic properties of the retinal rod outer segment disk ADP-ribosyl cyclase.
Vis. Neurosci. 28 , 121-128, (2011) Cyclic ADP-ribose (cADPR) is a second messenger modulating intracellular calcium levels. We have previously described a cADPR-dependent calcium signaling pathway in bovine rod outer segments (ROS), where calcium ions play a pivotal role. ROS ADP-ribosyl cycla... |
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The CD38-independent ADP-ribosyl cyclase from mouse brain synaptosomes: a comparative study of neonate and adult brain.
Biochem. J. 395(2) , 417-26, (2006) cADPR (cADP-ribose), a metabolite of NAD+, is known to modulate intracellular calcium levels and to be involved in calcium-dependent processes, including synaptic transmission, plasticity and neuronal excitability. However, the enzyme that is responsible for ... |
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The homo-dimeric form of ADP-ribosyl cyclase in solution.
Biochim. Biophys. Acta 1388(2) , 428-36, (1998) ADP-ribosyl cyclase is a multi-functional enzyme that catalyzes the formation of two Ca2+ signaling molecules, cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP). X-ray crystallography of three different crystal forms shows th... |
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Large-scale purification of Aplysia ADP-ribosylcyclase and measurement of its activity by fluorimetric assay.
Meth. Enzymol. 280 , 331-40, (1997)
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Hormonal control of ADP-ribosyl cyclase activity in pancreatic acinar cells from rats.
J. Biol. Chem. 278(36) , 33629-36, (2003) Cyclic ADP-ribose, a metabolite of NAD+ evokes Ca2+ release from intracellular stores in different cells. We have determined the activity of cADPr-producing enzymes (ADP-ribosyl cyclases) in different cellular fractions prepared from isolated pancreatic acina... |
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Synthesis of NAADP and cADPR in mitochondria.
Arch. Biochem. Biophys. 371(2) , 317-25, (1999) Here we investigated whether cADPR and NAADP are synthesized in mitochondria. We found that ADPR-cyclase activity is present in mitochondria. In addition, we describe for the first time synthesis of NAADP in this intracellular organelle. ADPR-cyclase activiti... |
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beta-NAD is a novel nucleotide released on stimulation of nerve terminals in human urinary bladder detrusor muscle.
Am. J. Physiol. Renal Physiol. 290(2) , F486-95, (2006) Endogenous nucleotides with extracellular functions may be involved in the complex neural control of human urinary bladder (HUB). Using HPLC techniques with fluorescence detection, we observed that in addition to ATP and its metabolites ADP, AMP and adenosine... |