SU4312
SU4312结构式
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常用名 | SU4312 | 英文名 | SU4312 |
|---|---|---|---|---|
| CAS号 | 5812-07-7 | 分子量 | 264.32200 | |
| 密度 | 1.219g/cm3 | 沸点 | 497.1ºC at 760 mmHg | |
| 分子式 | C17H16N2O | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 254.5ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Br. J. Pharmacol. 168(5) , 1201-14, (2013) SU4312, a potent and selective inhibitor of VEGF receptor-2 (VEGFR-2), has been designed to treat cancer. Recent studies have suggested that SU4312 can also be useful in treating neurodegenerative disorders. In this study, we assessed neuroprotection by SU431... |
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Automated image-based phenotypic analysis in zebrafish embryos.
Dev. Dyn. 238(3) , 656-63, (2009) Presently, the zebrafish is the only vertebrate model compatible with contemporary paradigms of drug discovery. Zebrafish embryos are amenable to automation necessary for high-throughput chemical screens, and optical transparency makes them potentially suited... |
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