2-羟基萨氯酚
2-羟基萨氯酚结构式
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常用名 | 2-羟基萨氯酚 | 英文名 | 2-hydroxysaclofen |
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| CAS号 | 117354-64-0 | 分子量 | 265.71400 | |
| 密度 | 1.551 g/cm3 | 沸点 | N/A | |
| 分子式 | C9H12ClNO4S | 熔点 | 267-269ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS05 |
信号词 | Danger |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Guide to Receptors and Channels (GRAC), 4th Edition.
Br. J. Pharmacol. 158 Suppl 1 , S1-254, (2009)
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Peripheral GABAB agonists stimulate gastric acid secretion in mice.
Br. J. Pharmacol. 142(6) , 1038-48, (2004) 1 We characterized the effects of intravenous GABA and preferential GABAA (muscimol), GABAB (R-baclofen and SKF-97541) and GABAC agonists (imidazole-4-acetic acid) on gastric acid secretion in urethane-anesthetized mice implanted with a gastric cannula, and d... |
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GABA receptors modulate trigeminovascular nociceptive neurotransmission in the trigeminocervical complex.
Br. J. Pharmacol. 134(4) , 896-904, (2001) 1. GABA (gamma-aminobutyric acid) receptors involved in craniovascular nociceptive pathways were characterised by in vivo microiontophoresis of GABA receptor agonists and antagonists onto neurones in the trigeminocervical complex of the cat. 2. Extracellular ... |
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Baclofen into the lateral parabrachial nucleus induces hypertonic sodium chloride intake during cell dehydration.
Behav. Brain Funct. 9 , 17, (2013) Activation of GABA(B) receptors with baclofen into the lateral parabrachial nucleus (LPBN) induces ingestion of water and 0.3 M NaCl in fluid replete rats. However, up to now, no study has investigated the effects of baclofen injected alone or combined with G... |
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Sequence dependence of post-tetanic potentiation after sequential heterosynaptic stimulation in the rat auditory cortex.
J. Physiol. 533(Pt 2) , 503-18, (2001) 1. To investigate the mechanisms for the coding stimulus sequence in the auditory cortex (AC), post-tetanic potentiation (PTP) was recorded after sequentially combined heterosynaptic stimulation was applied in rat AC slices. 2. Brief tetanic stimulation (TS) ... |
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Synaptic mechanisms regulating the activation of a Ca(2+)-mediated plateau potential in developing relay cells of the LGN.
J. Neurophysiol. 87(3) , 1175-85, (2002) Using intracellular recordings in an isolated (in vitro) rat brain stem preparation, we examined the synaptic responses of developing relay neurons in the dorsal lateral geniculate nucleus (LGN). In newborn rats, strong stimulation of the optic tract (OT) evo... |
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Theta-related gating cells in hippocampal formation: in vivo and in vitro study.
Hippocampus 23(1) , 30-9, (2013) In this study we extended our earlier in vitro findings concerning the discovery of a novel type of theta-related cells, which we have termed gating cells. There were two main objectives of our present investigations. The first was to determine the distributi... |
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Involvement of pallidothalamic circuitry in working memory.
Neuroscience 104(1) , 129-36, (2001) This study evaluated the capacity of mu-opioid and glutamate receptor agonists to differentially regulate the involvement of the GABAergic projection from the ventral pallidum to the mediodorsal thalamus in working memory and locomotor activity. Microinjectio... |
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Effects of GABAB receptor agonists and antagonists on glycemia regulation in mice.
Eur. J. Pharmacol. 677(1-3) , 188-96, (2012) γ-Aminobutyric acid (GABA) inhibits insulin secretion through GABA(B) receptors in pancreatic β-cells. We investigated whether GABA(B) receptors participated in the regulation of glucose homeostasis in vivo. BALB/c mice acutely pre-injected with the GABA(B) r... |