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α,β-亚甲基腺苷 5'-二磷酸 钠盐

α,β-亚甲基腺苷 5'-二磷酸 钠盐结构式
α,β-亚甲基腺苷 5'-二磷酸 钠盐结构式
品牌特惠专场
常用名 α,β-亚甲基腺苷 5'-二磷酸 钠盐 英文名 ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT
CAS号 104835-70-3 分子量 469.19200
密度 N/A 沸点 N/A
分子式 C11H15N5Na2O9P2 熔点 N/A
MSDS 美版 闪点 N/A

IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier.

Eur. J. Immunol. 38 , 2718-2726, (2008)

IFN-beta treatment reduces the relapse rate in MS but its mechanism of action remains incompletely understood. Our aim was to clarify the beneficial effect of IFN-beta in the treatment of MS. We assessed the influence of IFN-beta treatment on (i) CD73 express...

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression.

Eur. J. Immunol. 41 , 1231-1241, (2011)

CD73/ecto-5'-nucleotidase dephosphorylates extracellular AMP into adenosine, and it is a key enzyme in the regulation of adenosinergic signaling. The contribution of host CD73 to tumor growth and anti-tumor immunity has not been studied. Here, we show that un...

Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells.

Pharmacology 84 , 196-202, (2009)

Extracellular ATP may be metabolized to AMP and adenosine by the ectonucleotidases CD39 and CD73 and, in this study, we characterized the pathways for adenosine formation in human urinary tract epithelial cells.Bladder (RT4) and kidney (A498) epithelial cells...

Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.

Gastroenterology 135 , 1460-1462, (2008)