ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT

ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT Structure
ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT structure
Common Name ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT
CAS Number 104835-70-3 Molecular Weight 469.19200
Density N/A Boiling Point N/A
Molecular Formula C11H15N5Na2O9P2 Melting Point N/A
MSDS USA Flash Point N/A

IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier.

Eur. J. Immunol. 38 , 2718-2726, (2008)

IFN-beta treatment reduces the relapse rate in MS but its mechanism of action remains incompletely understood. Our aim was to clarify the beneficial effect of IFN-beta in the treatment of MS. We assessed the influence of IFN-beta treatment on (i) CD73 express...

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression.

Eur. J. Immunol. 41 , 1231-1241, (2011)

CD73/ecto-5'-nucleotidase dephosphorylates extracellular AMP into adenosine, and it is a key enzyme in the regulation of adenosinergic signaling. The contribution of host CD73 to tumor growth and anti-tumor immunity has not been studied. Here, we show that un...

Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells.

Pharmacology 84 , 196-202, (2009)

Extracellular ATP may be metabolized to AMP and adenosine by the ectonucleotidases CD39 and CD73 and, in this study, we characterized the pathways for adenosine formation in human urinary tract epithelial cells.Bladder (RT4) and kidney (A498) epithelial cells...

Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.

Gastroenterology 135 , 1460-1462, (2008)