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2-乙酰基-3-甲基噻吩

2-乙酰基-3-甲基噻吩结构式
2-乙酰基-3-甲基噻吩结构式
品牌特惠专场
常用名 2-乙酰基-3-甲基噻吩 英文名 2-Acetyl-3-methylthiophene
CAS号 13679-72-6 分子量 140.20300
密度 1.124 g/mL at 25 °C(lit.) 沸点 98-99 °C14 mm Hg(lit.)
分子式 C7H8OS 熔点 N/A
MSDS 中文版 美版 闪点 199 °F

Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition.

Eur. J. Med. Chem. 46(10) , 5138-45, (2011)

Hepatitis C virus (HCV) NS5B polymerase is a key target for anti-HCV therapeutics development. Here we report the synthesis and biological evaluation of a new series of α,γ-diketo acids (DKAs) as NS5B polymerase inhibitors. We initiated structure-activity rel...

Automated parallel synthesis of chalcone-based screening libraries. Powers DG, et al.

Tetrahedron 54(16) , 4085-96, (1998)