2-Acetyl-3-methylthiophene

2-Acetyl-3-methylthiophene Structure
2-Acetyl-3-methylthiophene structure
Common Name 2-Acetyl-3-methylthiophene
CAS Number 13679-72-6 Molecular Weight 140.20300
Density 1.124 g/mL at 25 °C(lit.) Boiling Point 98-99 °C14 mm Hg(lit.)
Molecular Formula C7H8OS Melting Point N/A
MSDS Chinese USA Flash Point 199 °F

Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition.

Eur. J. Med. Chem. 46(10) , 5138-45, (2011)

Hepatitis C virus (HCV) NS5B polymerase is a key target for anti-HCV therapeutics development. Here we report the synthesis and biological evaluation of a new series of α,γ-diketo acids (DKAs) as NS5B polymerase inhibitors. We initiated structure-activity rel...

Automated parallel synthesis of chalcone-based screening libraries. Powers DG, et al.

Tetrahedron 54(16) , 4085-96, (1998)