二苄胺
二苄胺结构式
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常用名 | 二苄胺 | 英文名 | Dibenzylamine |
|---|---|---|---|---|
| CAS号 | 103-49-1 | 分子量 | 197.28 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 300.0±0.0 °C at 760 mmHg | |
| 分子式 | C14H15N | 熔点 | −26 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 143.3±0.0 °C | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Spectrophotometric determination of folic acid in pharmaceutical preparations by coupling reactions with iminodibenzyl or 3-aminophenol or sodium molybdate-pyrocatechol.
Anal. Biochem. 307(2) , 316-21, (2002) Novel coupling reagents are used for the simple and sensitive spectrophotometric determination of folic acid either in pure form or in its pharmaceutical preparations. The methods are based on the probable diazotization of the p-aminobenzoylglutamic acid obta... |
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Diastereoselective construction of syn-α-oxyamines via three-component α-oxyaldehyde-dibenzylamine-alkyne coupling reaction: application in the synthesis of (+)-β-conhydrine and its analogues.
Org. Biomol. Chem. 10(37) , 7536-44, (2012) A Cu(I)-catalyzed α-oxyaldehyde-dibenzylamine-alkyne coupling reaction was delineated for the construction of α-oxyamines with excellent yields and diastereoselectivity. Crystal structure analysis and theoretical calculations were also supportive of the forma... |
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Kinetic study on the nitrosation of dibenzylamine in a model system.
Food Chem. Toxicol. 32(11) , 1015-9, (1994) A kinetic study of the formation of N-nitrosodibenzylamine (NDBzA), from the nitrosation of dibenzylamine (DBzA) by sodium nitrite, was performed in a model system under conditions (temperature, pH) that are similar to those encountered in the industrial prod... |
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Determination of imipramine in presence of iminodibenzyl and in pharmaceutical dosage form.
J. Pharm. Biomed. Anal. 33(4) , 775-82, (2003) Two spectrophotometric methods for the determination of imipramine in presence of iminodibenzyl as an impurity are described. The first method is a ratio-spectra first derivative spectrophotometry, the signals were measured at 240.2 nm for imipramine. Calibra... |
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The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core.
Bioorg. Med. Chem. Lett. 20(18) , 5544-7, (2010) The discovery of a series of novel and orally efficacious type II calcimimetics, developed from the lead compound 1, is described herein. Compound 22 suppressed plasma PTH levels relative to vehicle when dosed orally in a rat pharmacodynamic model.Copyright (... |
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Dapsone and iminodibenzyl as novel reagents for the spectrophotometric determination of trace amounts of nitrite in water samples.
Anal. Sci. 17(3) , 439-42, (2001) A rapid, simple, sensitive and selective spectrophotometric determination of nitrite using new diazotizing and coupling reagents is described. The method is based on a diazotization-coupling reaction between dapsone and iminodibenzyl in a hydrochloric acid me... |
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Dibenzylamine--a novel blocker of the voltage-dependent K+ current in myocardial mouse cells.
Naunyn Schmiedebergs Arch. Pharmacol. 364(1) , 9-13, (2001) Ventricular myocytes of the mouse ventricle were voltage clamped with a patch-clamp technique in the whole-cell configuration. At depolarizing voltage pulses, these myocytes develop a large voltage-dependent K+ outward current. Application of the drug dibenzy... |
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Determination of carbamazepine and its impurities iminostilbene and iminodibenzyl in solid dosage form by column high-performance liquid chromatography.
J. AOAC Int. 93(4) , 1059-68, (2010) An accurate and precise RP-HPLC method was developed and validated for the determination of carbamazepine and its impurities iminostilbene and iminodibenzyl in a tablet formulation with fluphenazine as an internal standard. Buffer-methanol (50 + 50, v/v) was ... |
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Pharmacokinetics of dibenzylamine administered in a sustained drug delivery system with cefazolin.
Biopharm. Drug Dispos. 11(9) , 797-806, (1990) The pharmacokinetics of dibenzylamine administered in a sustained drug delivery system with cefazolin was studied after i.m. administration of a dose of 1250 mg to healthy volunteers. The serum and urine levels of dibenzylamine were determined by a GLC techni... |
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Pharmacological and biochemical properties of iminodibenzyl antipsychotic drugs including Y-516 and clocapramine.
Clin. Neuropharmacol. 9 Suppl 4 , 319-21, (1986)
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