去羟米松
去羟米松结构式
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常用名 | 去羟米松 | 英文名 | Desoximetasone |
|---|---|---|---|---|
| CAS号 | 382-67-2 | 分子量 | 376.462 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 532.3±50.0 °C at 760 mmHg | |
| 分子式 | C22H29FO4 | 熔点 | 217ºC | |
| MSDS | 中文版 美版 | 闪点 | 275.7±30.1 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Warning |
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The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR mice.
Mol. Carcinog. 53(6) , 488-97, (2014) Glucocorticoids (GCs) are very effective at preventing carcinogen- and tumor promoter-induced skin inflammation, hyperplasia, and mouse skin tumor formation. The effects of GCs are mediated by a well-known transcription factor, the glucocorticoid receptor (GR... |
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Photosensitivity to desoximetasone emollient cream.
Arch. Dermatol. 124(12) , 1870-1, (1988)
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Rapid assay of the anti-inflammatory activity of topical corticosteroids by inhibition of a UVA-induced neutrophil infiltration in hairless mouse skin. II. Assessment of name brand versus generic potency.
Acta Derm. Venereol. 74(1) , 18-9, (1994) The hairless mouse model of a UVA-induced dermal neutrophilic infiltrate was used to compare the efficacy of equal concentrations of name brand versus generic corticosteroids. The generic brand was significantly less effective in suppressing the inflammatory ... |
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Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assay.
Skin Pharmacol. Physiol. 21(3) , 181-7, (2008) We report on a double-blind, vehicle-controlled, single-center confirmatory study with random assignment. The purpose of the study was to investigate the topical bioavailability of different topical corticosteroid formulations in healthy human beings focussin... |
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Spectrophotometric determination of desoximetasone in ointment using 1,4-dihydrazinophthalazine.
J. Pharm. Biomed. Anal. 14(8-10) , 947-50, (1996) The proposed method is based on coloured hydrazone formation with 1,4-dihydrazinophthalazine as a reagent. Heating at 85 degrees C for 2 h was found necessary to ensure optimal hydrazone formation in the presence of hydrochloric acid. The yellow hydrazone pro... |
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Cushing's syndrome from topical glucocorticoids.
West Indian Med. J. 42(2) , 77-8, (1993) A case of Cushing's syndrome is described in a woman who self-treated psoriasis with a variety of potent topical glucocorticoids over 15 years. She was successfully weaned off corticosteroids and was treated with alternative anti-psoriatic drugs. The disappea... |
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Iatrogenic hyperadrenocorticism and steatohepatitis caused by unapproved medicine.
Intern. Med. 47(13) , 1231-6, (2008) A 54-year-old man experienced weight gain. He was diagnosed as having hyperglycemia, hypertension and liver damage. Liver biopsy showed steatohepatitis. We initially suspected him as having hyperadrenocorticism. However, both adrenocorticotropic hormone and c... |
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Desoximetasone 0.25% and tacrolimus 0.1% ointments versus tacrolimus alone in the treatment of atopic dermatitis.
Cutis. 78(5) , 357-63, (2006) Long-term in vitro compatibility of desoximetasone and tacrolimus ointments prompted the current trial in humans. We aimed to evaluate the efficacy of twice-daily simultaneous application of desoximetasone and tacrolimus in the treatment of atopic dermatitis ... |
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A double-blind comparison of 0.25% and 0.05% desoxymethasone, 0.1% betamethasone valerate and 1% hydrocortisone creams in the treatment of eczema.
J. Int. Med. Res. 15(3) , 160-6, (1987) The efficacy and acceptability of 0.25% and 0.05% desoxymethasone, 0.1% betamethasone valerate and 1% hydrocortisone creams were compared in patients with eczema. A double-blind parallel group multi-centre design was employed in which 96 patients were recruit... |
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Diagnosis and treatment of radiation port dermatophytosis of scalp: a case report.
Mycoses 55(2) , e27-8, (2012)
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