盐酸雷莫司琼
盐酸雷莫司琼结构式
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常用名 | 盐酸雷莫司琼 | 英文名 | Ramosetron Hydrochloride |
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| CAS号 | 132907-72-3 | 分子量 | 315.797 | |
| 密度 | N/A | 沸点 | 579.7ºC at 760mmHg | |
| 分子式 | C17H18ClN3O | 熔点 | 244-246°C | |
| MSDS | 中文版 美版 | 闪点 | 304.4ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Inhibitory effect of ramosetron on corticotropin releasing factor- and soybean oil-induced delays in gastric emptying in rats.
J. Gastroenterol. Hepatol. 27(9) , 1505-11, (2012) Symptoms of functional dyspepsia (FD) are highly prevalent in patients with irritable bowel syndrome (IBS). However, the effects of therapeutic agents for IBS on the pathophysiology of FD are unclear. In this study, therefore, we examined the effects of ramos... |
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Efficacy of ramosetron in the treatment of male patients with irritable bowel syndrome with diarrhea: a multicenter, randomized clinical trial, compared with mebeverine.
Neurogastroenterol. Motil. 23(12) , 1098-104, (2011) The 5-HT(3) receptor antagonists are known to be effective for the treatment of diarrhea-predominant irritable bowel syndrome (IBS), but not widely used yet. The aim of this study was to compare the efficacy and safety of ramosetron, a 5-HT(3) receptor antago... |
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Treatment of IBS-D with 5-HT3 receptor antagonists vs spasmolytic agents: similar therapeutical effects from heterogeneous pharmacological targets.
Neurogastroenterol. Motil. 23(12) , 1051-5, (2011) There is still no agreement over optimal pharmacological treatment for irritable bowel syndrome (IBS). Patients with IBS and diarrhea (IBS-D) demonstrate both visceral hypersensitivity and impaired colonic motility with increased frequency and amplitude of gi... |
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Comparison of the efficacy of ramosetron and ondansetron in the prophylaxis of postoperative vomiting in children receiving fentanyl by patient-controlled analgesia after orthopedic surgery: a randomized controlled trial.
Paediatr. Anaesth. 23(4) , 360-4, (2013) This study was designed to compare the efficacy of prophylactic ramosetron and ondansetron in preventing postoperative vomiting in children who received fentanyl by patient-controlled analgesia after orthopedic surgery.Two hundred and eighteen children, 2-15 ... |
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Reevaluation of the effectiveness of ramosetron for preventing postoperative nausea and vomiting: a systematic review and meta-analysis.
Anesth. Analg. 117(2) , 329-39, (2013) Ramosetron has been shown to have a very strong effect for preventing postoperative nausea and vomiting (PONV) in previous meta-analyses. However, these previous meta-analyses included a number of studies by Fujii et al. which have now been proven to have bee... |
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Prophylactic control of post-operative nausea and vomiting using ondansetron and ramosetron after cardiac surgery.
Acta Anaesthesiol. Scand. 54(8) , 962-9, (2010) The aim of this study was to evaluate the efficacy of ondansetron and ramosetron in the reduction of post-operative nausea and vomiting (PONV) associated with patient-controlled analgesia (PCA) after cardiac surgery.A total of 320 patients scheduled for elect... |
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Ramosetron vs. ramosetron plus dexamethasone for the prevention of postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy: prospective, randomized, and double-blind study.
Int. J. Surg. 11(2) , 183-7, (2013) Up to 75% of the patients undergoing laparoscopic cholecystectomy develop postoperative nausea and vomiting (PONV). Both ramosetron, a serotonin subtype 3 (5-HT3) antagonist, and dexamethasone are effective for PONV prophylaxis following laparoscopic cholecys... |
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Intravenous, oral, and the combination of intravenous and oral ramosetron for the prevention of nausea and vomiting after laparoscopic cholecystectomy: a randomized, double-blind, controlled trial.
Clin. Ther. 33(9) , 1162-72, (2011) Patients undergoing general anesthesia for laparoscopic cholecystectomy have a high risk of postoperative nausea and vomiting (PONV) with incidences up to 75%. Ramosetron, a serotonin subtype 3 (5-HT(3)) antagonist, has been shown to be effective as an antiem... |
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Effects of ramosetron and dexamethasone on postoperative nausea, vomiting, pain, and shivering in female patients undergoing thyroid surgery.
J. Anesth. 27(1) , 29-34, (2013) Some antiemetics are effective in the treatment of postoperative pain and shivering, as well as for postoperative nausea and vomiting (PONV). The aim of this study was to investigate the effects of ramosetron and dexamethasone on PONV, pain, and shivering and... |
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Ramosetron, midazolam, and combination of ramosetron and midazolam for prevention of postoperative nausea and vomiting: a prospective, randomized, double-blind study.
J. Int. Med. Res. 41(4) , 1203-13, (2013) To compare the efficacy of ramosetron, midazolam, and the combination of ramosetron and midazolam in the prevention of postoperative nausea and vomiting (PONV) in female patients undergoing thyroidectomy.Patients were randomized to receive 0.3 mg ramosetron (... |