2-氯-4,6-二甲氧基-1,3,5-三嗪
2-氯-4,6-二甲氧基-1,3,5-三嗪结构式
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常用名 | 2-氯-4,6-二甲氧基-1,3,5-三嗪 | 英文名 | 2-Chloro-4,6-dimethoxy-1,3,5-triazine |
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| CAS号 | 3140-73-6 | 分子量 | 175.57 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 305.1±25.0 °C at 760 mmHg | |
| 分子式 | C5H6ClN3O2 | 熔点 | 71-74 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 138.3±23.2 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Towards the chiral metabolomics: Liquid chromatography-mass spectrometry based DL-amino acid analysis after labeling with a new chiral reagent, (S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl)pyrrolidine-2-carboxylate, and the application to saliva of healthy volunteers.
Anal. Chim. Acta 875 , 73-82, (2015) A novel triazine-type chiral derivatization reagent, i.e., (S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate (DMT-(S)-Pro-OSu), was developed for the highly sensitive and selective detection of chiral amines and amino... |
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Study on 1,3,5-triazine chemistry in dehydrocondensation: gauche effect on the generation of active triazinylammonium species.
Chemistry 18(49) , 15856-67, (2012) The reaction of 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) with various nitrogen-containing compounds, particularly tertiary amines (tert-amines), has been studied for the preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts [DMT-Am(s)]. D... |
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Study of 1,3,5-triazine-based catalytic amide-forming reactions: effect of solvents and basicity of reactants.
Chem. Pharm. Bull. 61(8) , 882-6, (2013) Effect of the basic property of reactants (tertiary amine catalysts, a substrate amine, and acid neutralizers) on catalytic dehydrocondensation between a carboxylic acid and an amine by using 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) was studied. The react... |
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Bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether as coupling reagent for peptide synthesis.
Chem. Biodivers. 10(5) , 952-61, (2013) Bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether (4) was prepared by treatment of 2-hydroxy-4,6-dimethoxy-1,3,5-triazine with 2-chloro-4,6-dimethoxy-1,3,5-triazine in 61% yield. Ether 4, isoelectronic with pyrocarbonates, was found capable to activate carboxylic a... |
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Specific labeling of streptavidin for better understanding of ligand modification in modular method for affinity labeling (MoAL).
Chem. Pharm. Bull. 62(11) , 1146-50, (2014) We studied the specific labeling of streptavidin using the modular method for affinity labeling (MoAL) that we developed based on a catalytic amide-forming reaction using 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) and a tertiary amine catalyst. The primary ... |
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Labeling study of avidin by modular method for affinity labeling (MoAL).
Bioorg. Med. Chem. Lett. 20 , 7050-3, (2010) We studied the specific labeling of avidin with biotinylated modular ligand catalysts via MoAL, which we recently established. The labeling yield was found to depend on the linker length connecting the catalytic site to biotin in the modular ligand catalyst 1... |
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Synthesis , 917, (1987)
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An improved procedure for the large scale preparation of 2-chloro-4, 6-dimethoxy-1, 3, 5-triazine. Cronin JS, et al.
Synth. Commun. 26(!8) , 3491-94, (1996)
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4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride: an efficient condensing agent leading to the formation of amides and esters. Kunishima M, et al.
Tetrahedron 55(46) , 13159-70, (1999)
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2-Chloro-4, 6-dimethoxy-1, 3, 5-triazine. A new coupling reagent for peptide synthesis. Kaminski ZJ.
Synthesis 10 , 917-20, (1987)
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