异佛尔酮二异氰酸酯
一般危化品
异佛尔酮二异氰酸酯结构式
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常用名 | 异佛尔酮二异氰酸酯 | 英文名 | UNII:43B0856528 |
|---|---|---|---|---|
| CAS号 | 4098-71-9 | 分子量 | 222.283 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 286.9±13.0 °C at 760 mmHg | |
| 分子式 | C12H18N2O2 | 熔点 | -60°C | |
| MSDS | 中文版 美版 | 闪点 | 116.0±25.2 °C | |
| 符号 |
GHS06, GHS08, GHS09 |
信号词 | Danger |
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Correlating cell transfectability and motility on materials with different physico-chemical properties.
Acta Biomater. 28 , 55-63, (2015) Gene delivery into cells can be facilitated by adding plasmid DNA/transfection reagent complexes in culture medium or pre-adsorbing the complexes on the substrate before cell seeding. Using transfection reagents, however, often causes cytotoxicity. Effective ... |
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Modelling the surface free energy parameters of polyurethane coats-part 1. Solvent-based coats obtained from linear polyurethane elastomers.
Colloid Polym. Sci. 291(4) , 1031-1047, (2013) Polyurethane elastomers coating were synthesised by using typical diisocyanates, polyether and polyester polyols and HO-tertiary amines or diols as a chain extenders. Mole fractions of structural fragments (_ exp) responsible for the polar interactions within... |
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Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein?
Nat. Prod. Commun. 10 , 951-4, (2015) In recent years polyurethane microstructures (PM) have gained increasing attention in the pharmaceutical field due to the importance of their practical application. Since finding that such a formulation with genistein could improve its applications, we have c... |
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New injectable elastomeric biomaterials for hernia repair and their biocompatibility.
Biomaterials 75 , 182-92, (2015) Complications associated with implantation of polymeric hernia meshes remain a difficult surgical challenge. We report here on our work, developing for the first time, an injectable viscous material that can be converted to a solid and elastic implant in vivo... |
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Molecular engineering of manipulated alginate-based polyurethanes.
Carbohydr. Polym. 112 , 638-47, (2014) The novel soluble alginate-based polyurethanes in organic solvents were synthesized by the reaction of NCO-terminated prepolymers and tributylammonium alginate (TBA-Alg) for the first time. The chemical structures of synthesized polyurethanes were characteriz... |
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Occupational contact allergy to monomeric isocyanates.
Contact Dermatitis 67(2) , 78-88, (2012) The monomeric isocyanates diphenylmethane diisocyanate (MDI), 2,4-toluene diisocyanate (TDI), isophorone diisocyanate (IPDI) and 1,6-hexamethylene diisocyanate (HDI) are used in polyurethane products and sometimes cause contact allergy.To describe patients wi... |
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Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles.
Int. J. Nanomedicine 10 , 4565-80, (2015) Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitiv... |
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Migrating components in a polyurethane laminating adhesive identified using gas chromatography/mass spectrometry.
Rapid Commun. Mass Spectrom. 26(16) , 1810-6, (2012) Plastics are increasingly used as packaging materials for pharmaceuticals. However, diffusion of compounds in plastic into drugs may endanger patients' health. Regulatory authorities therefore demand detailed information about leachable compounds in plastics.... |
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Allergic contact dermatitis from dicyclohexylmethane-4,4'-diisocyanate.
Contact Dermatitis 48(6) , 305-9, (2003) From August 1999 to April 2001, there was an outbreak of severe eczema at a factory manufacturing medical equipment. A glue, mainly based on the isocyanate dicyclohexylmethane-4,4'-diisocyanate (DMDI), was suspected as being the cause of the problem. 16 worke... |
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Characterization of murine immune responses to allergenic diisocyanates.
Toxicol. Appl. Pharmacol. 112(2) , 190-7, (1992) Chemicals may cause contact allergy. Some allergens may, in addition, cause respiratory sensitization. In previous investigations we have found that contact and respiratory sensitizers induce differential immune responses in mice characteristic of TH1 and TH2... |