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碘酸钠

一般危化品
碘酸钠结构式
碘酸钠结构式
常用名 碘酸钠 英文名 Sodium iodate
CAS号 7681-55-2 分子量 197.892
密度 4.28 g/mL at 25 °C(lit.) 沸点 N/A
分子式 INaO3 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS03 GHS07 GHS08
GHS03, GHS07, GHS08
信号词 Danger

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

Nat. Commun. 5 , 3793, (2014)

Myogenic regulatory factors such as MyoD and Myf5 lie at the core of vertebrate muscle differentiation. However, E-boxes, the cognate binding sites for these transcription factors, are not restricted to the promoters/enhancers of muscle cell-specific genes. T...

Resveratrol protects RPE cells from sodium iodate by modulating PPARα and PPARδ.

Exp. Eye Res. 118 , 100-8, (2014)

Selective killing of RPE cells in vivo by sodium iodate develops cardinal phenotypes of atrophic age-related macular degeneration. However, the molecular mechanisms are elusive. We tried to search for small cyto-protective molecules against sodium iodate and ...

H9 Inhibits Tumor Growth and Induces Apoptosis via Intrinsic and Extrinsic Signaling Pathway in Human Non-Small Cell Lung Cancer Xenografts.

J. Microbiol. Biotechnol. 25 , 648-57, (2015)

H9, a novel herbal extract, demonstrated cytotoxicity in A549 non-small cell lung cancer (NSCLC) cell lines. In this study, we investigated whether H9, and/or co-treatment with an anticancer drug, pemetrexed (PEM), inhibited tumor growth in BALB/c nude mice m...

Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage.

Exp. Eye Res. 97(1) , 137-47, (2012)

Our purpose was to find a method to create a large animal model of inducible photoreceptor damage. To this end, we tested in domestic swine the efficacy of two chemical toxins, known to create photoreceptor damage in other species: Iodoacetic Acid (IAA) and S...

Dose-dependent retinal changes following sodium iodate administration: application of spectral-domain optical coherence tomography for monitoring of retinal injury and endogenous regeneration.

Curr. Eye Res. 39(10) , 1033-41, (2014)

The purpose of this study was to demonstrate the progression of acute retinal injury by correlating histological sections with in vivo spectral-domain optical coherence tomography (SD-OCT) images.Male C57BL/6 mice were treated intravenously with two different...

Manganese-enhanced MRI studies of alterations of intraretinal ion demand in models of ocular injury.

Invest. Ophthalmol. Vis. Sci. 48(8) , 3796-804, (2007)

To provide proof-of-concept that the extent of intraretinal manganese uptake after systemic MnCl(2) injection, detected with manganese-enhanced MRI (MEMRI), assesses alterations in intraretinal ion demand in models of ocular insult.In Sprague-Dawley rats, ret...

Decreased visual function after patchy loss of retinal pigment epithelium induced by low-dose sodium iodate.

Invest. Ophthalmol. Vis. Sci. 50(8) , 4004-10, (2009)

To correlate damage to the retinal pigment epithelium (RPE) with decreased visual function after the systemic administration of sodium iodate (NaIO(3)).Damage was produced in mice by injection of 15, 25, or 35 mg/kg NaIO(3). Visual function was assessed with ...

Systemically transferred hematopoietic stem cells home to the subretinal space and express RPE-65 in a mouse model of retinal pigment epithelium damage.

Exp. Eye Res. 83(5) , 1295-302, (2006)

Stem cell regeneration of damaged tissue has recently been reported in many different organs. Since the loss of retinal pigment epithelium (RPE) in the eye is associated with a major cause of visual loss - specifically, age-related macular degeneration - we i...

[Functional improvement of injured retina following the adjuvant stem cell-based therapy. Preliminary report].

Klin. Oczna 113(4-6) , 117-21, (2011)

The purpose of this study was to appraise the functional response of damaged retina to the stem cell-based therapy in mice. The majority of disorders leading to the irreversible vision loss in the developed world is caused by retinal degeneration. Since, rece...

Comparison of radiohaloanalogues of meta-iodobenzylguanidine (MIBG) for a combined gene- and targeted radiotherapy approach to bladder carcinoma.

Med. Chem. 1(6) , 611-8, (2005)

Targeted radiotherapy using radiolabelled meta-iodobenzylguanidine (MIBG) is a promising treatment option for bladder cancer, restricting the effects of radiotherapy to malignant cells thereby increasing efficacy and decreasing morbidity of radiotherapy. We i...