COMPLEMENT FACTOR H 来源于人类血浆
COMPLEMENT FACTOR H 来源于人类血浆结构式
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常用名 | COMPLEMENT FACTOR H 来源于人类血浆 | 英文名 | FACTOR H, HUMAN |
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| CAS号 | 80295-65-4 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Outer membrane protein OlpA contributes to Moraxella catarrhalis serum resistance via interaction with factor H and the alternative pathway.
J. Infect. Dis. 210(8) , 1306-10, (2014) Factor H is an important complement regulator of the alternative pathway commonly recruited by pathogens to achieve increased rates of survival in the human host. The respiratory pathogen Moraxella catarrhalis, which resides in the mucosa, is highly resistant... |
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Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study.
Ophthalmology 122(1) , 162-9, (2015) To evaluate the impact of complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) risk alleles on the observed response to components of the Age-Related Eye Disease Study (AREDS) formulation.Genetic and statistical subgroup analysis of ... |
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Structural basis for sialic acid-mediated self-recognition by complement factor H.
Nat. Chem. Biol. 11(1) , 77-82, (2015) The serum protein complement factor H (FH) ensures downregulation of the complement alternative pathway, a branch of innate immunity, upon interaction with specific glycans on host cell surfaces. Using ligand-based NMR, we screened a comprehensive set of sial... |
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Complement profile in neonates of different gestational ages.
Scand. J. Immunol. 79(4) , 276-81, (2014) Blood levels of regulators of the complement system in preterm babies were reported in few studies only. The aim of this study was to set up a complement profile in premature and term babies focusing on the development of blood levels of MBL, key regulatory p... |
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TheIL-8,VEGF, andCFHPolymorphisms and Bevacizumab in Age-related Macular Degeneration
Ophthalmology 121(4) , 973-973.e1, (2014)
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Risk characteristics of the combined geographic atrophy and choroidal neovascularisation phenotype in age-related macular degeneration.
Br. J. Ophthalmol. 98(12) , 1729-32, (2014) To investigate the risk characteristics of the combined geographic atrophy (GA) and choroidal neovascularisation (CNV) phenotype of age-related macular degeneration (AMD) compared to GA or CNV.Patients with advanced AMD were identified and divided into three ... |
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Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum.
Proc. Natl. Acad. Sci. U. S. A. 111(1) , 427-32, (2014) The complement system is a crucial component of the innate immune response against invading bacterial pathogens. The human pathogen Neisseria meningitidis (Nm) is known to possess several mechanisms to evade the complement system, including binding to complem... |
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Immune evasion of Enterococcus faecalis by an extracellular gelatinase that cleaves C3 and iC3b.
J. Histochem. Cytochem. 181 , 6328-36, (2008) Enterococcus faecalis (Ef) accounts for most cases of enterococcal bacteremia, which is one of the principal causes of nosocomial bloodstream infections (BSI). Among several virulence factors associated with the pathogenesis of Ef, an extracellular gelatinase... |
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CFH and ARMS2 genetic polymorphisms predict response to antioxidants and zinc in patients with age-related macular degeneration.
Ophthalmology 120(11) , 2317-23, (2013) The Age-Related Eye Disease Study (AREDS) demonstrated that antioxidant and zinc supplementation decreases progression to advanced age-related macular degeneration (AMD) in patients with moderate to severe disease. We evaluated the interaction of genetics and... |
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A potential anti-coagulant role of complement factor H
Mol. Immunol. 59(2) , 188-93, (2014) Anti-phospholipid syndrome (APS) is a complex autoimmune disease, associated with recurrent venous and arterial thrombosis in various tissues. APS is associated with specific antibodies against plasma beta-2 glycoprotein 1 (β2-GP1), and these antibodies react... |