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咪唑-4-甲酸钠

咪唑-4-甲酸钠结构式
咪唑-4-甲酸钠结构式
品牌特惠专场
常用名 咪唑-4-甲酸钠 英文名 Sodium 2-(1H-imidazol-4-yl)acetate
CAS号 56368-58-2 分子量 148.1
密度 N/A 沸点 N/A
分子式 C5H5N2NaO2 熔点 N/A
MSDS 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier.

PLoS ONE 9(6) , e99449, (2014)

Development of effective non-viral vectors is of crucial importance in the implementation of RNA interference in clinical routine. The localized delivery of siRNAs to the gastrointestinal mucosa is highly desired but faces specific problems such as the stabil...

Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc.

Proc. Natl. Acad. Sci. U. S. A. 105(37) , 13793-8, (2008)

Protein GlcNAcylation serves as a nutrient/stress sensor to modulate the functions of many nuclear and cytoplasmic proteins. O-GlcNAc cycles on serine or threonine residues like phosphorylation, is nearly as abundant, and functions, at least partially, via it...

Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities.

J. Physiol. 581(Pt 3) , 1001-18, (2007)

The onset of motor learning in rats coincides with exclusive expression of GABAA receptors containing alpha6 and delta subunits in the granule neurons of the cerebellum. This development temporally correlates with the presence of a spontaneously active chlori...

Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol.

Proteomics 5(17) , 4376-88, (2005)

IMAC can be used to selectively enrich phosphopeptides from complex peptide mixtures, but co-retention of acidic peptides together with the failure to retain some phosphopeptides restricts the general utility of the method. In this study Fe(III)-IMAC was qual...

Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation.

Biochemistry 44(19) , 7378-87, (2005)

Hypochlorous acid (HOCl) is a powerful oxidant generated from H(2)O(2) and chloride ions by the heme enzyme myeloperoxidase (MPO) released from activated leukocytes. In addition to its potent antibacterial effects, excessive HOCl production can lead to host t...

Peripheral GABAB agonists stimulate gastric acid secretion in mice.

Br. J. Pharmacol. 142(6) , 1038-48, (2004)

1 We characterized the effects of intravenous GABA and preferential GABAA (muscimol), GABAB (R-baclofen and SKF-97541) and GABAC agonists (imidazole-4-acetic acid) on gastric acid secretion in urethane-anesthetized mice implanted with a gastric cannula, and d...

Theoretical studies of IMAC interfacial phenomena for the production of protein C.

Adv. Exp. Med. Biol. 540 , 183-90, (2003)

Characterization of phosphorylation sites on Tpl2 using IMAC enrichment and a linear ion trap mass spectrometer.

J. Proteome Res. 6(6) , 2269-76, (2007)

Advances in analytical techniques, specifically in mass spectrometry, have allowed for both facile protein identification and routine sequencing of proteins at increased sensitivity levels. Protein modifications present additional challenges because they occu...

Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening.

J. Biol. Chem. 277(46) , 43741-8, (2002)

Mutagenesis of recombinant rho1 gamma-aminobutyric acid (GABA) receptors has previously identified five residues in the amino terminal extracellular domain that play an important role in GABA binding. Here, we present evidence that the tyrosine at position 10...

Towards crystallization of hydrophobic myelin glycoproteins: P0 and PASII/PMP22.

Protein Expr. Purif. 26(3) , 368-77, (2002)

The preparation of a pure and homogeneous protein sample at proper concentration is a prerequisite for success when attempting their crystallization for structural determination. The detergents suitable for solubilization particularly of membrane proteins are...