溴化氰活化的琼脂糖
溴化氰活化的琼脂糖结构式
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常用名 | 溴化氰活化的琼脂糖 | 英文名 | Cyanogen bromide-activated Agarose |
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| CAS号 | 68987-32-6 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis.
Sci. Rep. 5 , 12332, (2015) Human profilin-1 is a novel protein associated with a recently discovered form of familial amyotrophic lateral sclerosis. This urges the characterization of possible conformational states, different from the fully folded state, potentially able to initiate se... |
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Novel glycan biomarkers for the detection of lung cancer.
J. Proteome Res. 10(4) , 1755-1764, (2011) Lung cancer has a poor prognosis and a 5-year survival rate of 15%. Therefore, early detection is vital. Diagnostic testing of serum for cancer-associated biomarkers is a noninvasive detection method. Glycosylation is the most frequent post-translational modi... |
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Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.
Nat. Neurosci. 13(11) , 1396-1403, (2010) Many mutations confer one or more toxic function(s) on copper/zinc superoxide dismutase 1 (SOD1) that impair motor neuron viability and cause familial amyotrophic lateral sclerosis (FALS). Using a conformation-specific antibody that detects misfolded SOD1 (C4... |
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Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Science 335 , 225-228, (2012) The cytokine tumor necrosis factor (TNF) is the primary trigger of inflammation. Like many extracellular signaling proteins, TNF is synthesized as a transmembrane protein; the active signal is its ectodomain, which is shed from cells after cleavage by an ADAM... |
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Transforming growth factor beta (TGFB) signaling is activated during porcine implantation: proposed role for latency-associated peptide interactions with integrins at the conceptus-maternal interface.
Reproduction 139 , 465-478, (2010) The process of implantation is mediated by a complex network of signaling and adhesive factors. In the pig, latent and active transforming growth factor beta (TGFB), TGFB receptors (TGFBR), and integrins (ITGs) are present during the peri-implantation period.... |
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The farnesyl-diphosphate/geranylgeranyl-diphosphate synthase of Toxoplasma gondii is a bifunctional enzyme and a molecular target of bisphosphonates.
J. Biol. Chem. 282(42) , 30804-30816, (2007) Farnesyl-diphosphate synthase (FPPS) catalyzes the synthesis of farnesyl diphosphate, an important precursor of sterols, dolichols, ubiquinones, and prenylated proteins. We report the cloning and characterization of two Toxoplasma gondii farnesyl-diphosphate ... |
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Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice.
Mol. Cell. Biol. 24(11) , 5080-5087, (2004) Phosphorylated derivatives of the lipid phosphatidylinositol are known to play critical roles in insulin response. Phosphatidylinositol 5-phosphate 4-kinases convert phosphatidylinositol 5-phosphate to phosphatidylinositol 4,5-bis-phosphate. To understand the... |
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Action of human group IIa secreted phospholipase A2 on cell membranes. Vesicle but not heparinoid binding determines rate of fatty acid release by exogenously added enzyme.
J. Biol. Chem. 273(48) , 32142-32153, (1998) Human group IIa phospholipase A2 (hIIa-PLA2) is a highly basic protein that is secreted from a number of cells during inflammation and may play a role in arachidonate liberation and in destruction of invading bacteria. It has been proposed that rodent group I... |
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Immobilization of invertase on sepharose-linked enzyme glycosyl recognizing polyclonal antibodies.
Biotechnol. Bioeng. 56 , 605-609, (1997) Polyclonal antibodies directed against the yeast invertase glycosyls were raised by immunizing rabbits with neoglycoprotein-I and neoglycoprotein-II. The neoglycoproteins were prepared by separately coupling the N-linked large and small molecular weight yeast... |
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An electrochemiluminescence-based competitive displacement immunoassay for the type-2 brevetoxins in oyster extracts.
J. AOAC Int. 90(1) , 173-178, (2007) A new competitive electrochemiluminescence-based immunoassay for the type-2 brevetoxins in oyster extracts was developed. The assay was verified by spiking known amounts of PbTx-3 into 80% methanol extracts of Gulf Coast oysters. We also provide preliminary d... |