一水肌酸
一水肌酸结构式
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常用名 | 一水肌酸 | 英文名 | 2-(1-Methylguanidino)acetic acid hydrate |
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| CAS号 | 6020-87-7 | 分子量 | 149.148 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C4H11N3O3 | 熔点 | 292 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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In-line coupling of single-drop microextraction with capillary electrophoresis-mass spectrometry.
Anal. Bioanal. Chem 407 , 8745-52, (2015) Single-drop microextraction (SDME) was in-line coupled with capillary electrophoresis-mass spectrometry to provide sample cleanup and enrichment simultaneously. Since there is no outlet vial in a conventional capillary electrophoresis-electrospray ionization-... |
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Creatine is a scavenger for methylglyoxal under physiological conditions via formation of N-(4-methyl-5-oxo-1-imidazolin-2-yl)sarcosine (MG-HCr).
J. Agric. Food Chem. 63(8) , 2249-56, (2015) Following incubation of methylglyoxal and creatine under physiological conditions, N-(4-methyl-5-oxo-1-imidazolin-2-yl)sarcosine (MG-HCr) was isolated and identified by NMR and mass spectrometry. Due to its rapid formation, MG-HCr represents a specific produc... |
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Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart.
PLoS ONE 9(10) , e109021, (2014) Multiple studies suggest creatine mediates anti-oxidant activity in addition to its established role in cellular energy metabolism. The functional significance for the heart has yet to be established, but antioxidant activity could contribute to the cardiopro... |
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Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity.
FASEB J. 29 , 2397-411, (2015) Firmicutes and Bacteroidetes, 2 major phyla of gut microbiota, are involved in lipid and bile acid metabolism to maintain systemic energy homeostasis in host. Recently, accumulating evidence has suggested that dietary changes promptly induce the alteration of... |
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Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis.
Proc. Natl. Acad. Sci. U. S. A. 110(49) , 19820-5, (2013) Mucosal surfaces of the lower gastrointestinal tract are subject to frequent, pronounced fluctuations in oxygen tension, particularly during inflammation. Adaptive responses to hypoxia are orchestrated largely by the hypoxia-inducible transcription factors (H... |
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Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations.
Nucleic Acids Res. 44 , 1449-70, (2016) Duchenne muscular dystrophy (DMD) is a fatal X-linked muscle-wasting disorder caused by mutations in the 2.4 Mb dystrophin-encoding DMD gene. The integration of gene delivery and gene editing technologies based on viral vectors and sequence-specific designer ... |
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Creatine supplementation enhances corticomotor excitability and cognitive performance during oxygen deprivation.
J. Neurosci. 35(4) , 1773-80, (2015) Impairment or interruption of oxygen supply compromises brain function and plays a role in neurological and neurodegenerative conditions. Creatine is a naturally occurring compound involved in the buffering, transport, and regulation of cellular energy, with ... |
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Estimated carrier frequency of creatine transporter deficiency in females in the general population using functional characterization of novel missense variants in the SLC6A8 gene.
Gene 565 , 187-91, (2015) Creatine transporter deficiency (CRTR-D) is an X-linked inherited disorder of creatine transport. All males and about 50% of females have intellectual disability or cognitive dysfunction. Creatine deficiency on brain proton magnetic resonance spectroscopy and... |
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Interactions of aging, overload, and creatine supplementation in rat plantaris muscle.
J. Aging Res. 2011 , 393416, (2011) Attenuation of age-related sarcopenia by creatine supplementation has been equivocal. In this study, plantaris muscles of young (Y; 5m) and aging (A; 24m) Fisher 344 rats underwent four weeks of either control (C), creatine supplementation (Cr), surgical over... |